Enrichment of a fraction toxic to guinea-pigs from Pachystigma pygmaeum (Schltr.) Robyns
| dc.contributor.author | Patterton, H.G. | |
| dc.contributor.author | Potgieter, D.J.J. | |
| dc.contributor.editor | Bigalke, R.D. | |
| dc.contributor.upauthor | Verschoor, Jan Adrianus | |
| dc.date.accessioned | 2015-04-02T06:55:29Z | |
| dc.date.available | 2015-04-02T06:55:29Z | |
| dc.date.created | 2014 | |
| dc.date.issued | 1985 | |
| dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en_ZA |
| dc.description.abstract | Pachystigma pygmaeum is one of several species of rubiaceous plants which cause delayed heart failure among ruminants after their ingestion at relatively high doses. Using guinea-pigs for toxicity determinations, we were able to separate and enrich a toxic fraction from a fermentation extract of the plant material by countercurrent distribution. It contained virtually no potassium salts, passed through a 500 dalton selective membrane, exhibited lability under acid conditions and was toxic at 1 g/kg per os, with a delayed response of 3-4 days. | en_ZA |
| dc.description.sponsorship | Department of Agriculture. | en_ZA |
| dc.identifier.citation | Verschoor, J.A., Patterton, H.G. & Potgieter, D.J.J. 1985, 'Enrichment of a fraction toxic to guinea-pigs from Pachystigma pygmaeum (Schltr.) Robyns’, Onderstepoort Journal of Veterinary Research, vol. 52, no. 2, pp. 101-104. | en_ZA |
| dc.identifier.issn | 0330-2465 | |
| dc.identifier.uri | http://hdl.handle.net/2263/44234 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Published by The Government Printer, Pretoria | en_ZA |
| dc.rights | ©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital). | en_ZA |
| dc.subject | Veterinary medicine | en_ZA |
| dc.subject.lcsh | Veterinary medicine -- South Africa | |
| dc.title | Enrichment of a fraction toxic to guinea-pigs from Pachystigma pygmaeum (Schltr.) Robyns | en_ZA |
| dc.type | Article | en_ZA |