Novel therapies in the management of food allergy : oral immunotherapy and anti-IgE

Show simple item record Gray, Claudia L. Goddard, E. Karabus, S. Kriel, M. Lang, A.C. Manjra, Ahmed I. Risenga, Samuel Malamulele Terblanche, Alta J. Van der Spuy, D.A. Levin, M.E. 2015-03-03T06:05:01Z 2015-03-03T06:05:01Z 2015-01
dc.description.abstract The process of oral immunotherapy (OIT) consists of a series of dose escalations with the immediate goal of inducing desensitisation and ultimately achieving a state of tolerance. Owing to the limitations of OIT, including side-effects and lack of proven efficacy in long-term tolerance induction, it is not yet recommended in routine clinical practice and should be restricted to the research setting. Studies using anti-immunoglobulin E (IgE) antibody in food allergy management are limited, but show promising results. The possible applications are for increasing the sensitivity threshold to certain foods such as peanut, and also for use in combination with OIT to enhance safety and rapidity of the OIT process; however, anti-IgE is not yet licensed for use in food allergy. en_ZA
dc.description.librarian hb2015 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Gray, CL, Goddard, E, Karabus, S & Kriel, M 2015, 'Novel therapies in the management of food allergy : oOral immunotherapy and anti-IgE', South African Medical Journal, vol. 105, no. 1, pp. 72-73. en_ZA
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAMJ.9105
dc.language.iso en en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights © 2015 Health & Medical Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0). en_ZA
dc.subject Food allergies en_ZA
dc.subject Oral immunotherapy (OIT) en_ZA
dc.subject Anti-immunoglobulin E (IgE) en_ZA
dc.subject Food allergy management en_ZA
dc.title Novel therapies in the management of food allergy : oral immunotherapy and anti-IgE en_ZA
dc.type Article en_ZA

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