The articles in this issue of CME reflect the views of a number of individuals who developed the guideline for the management of atopic dermatitis (AD) to improve the outcome of its treatment in South Africa (SA). AD has a major impact on the quality of life of sufferers and it is hoped that the articles and the guidelines they embody, if implemented, play a role in achieving these outcomes. Not only is AD the most common skin disease in children, but it causes tremendous morbidity. Engaging with many of these suffering children and their parents daily, is emotionally draining and energy sapping. No other skin condition places such demands on resources, time and the human spirit.