dc.contributor.author |
Behrens, Dieter
|
|
dc.contributor.author |
Moritz, Robin F.A.
|
|
dc.date.accessioned |
2014-10-02T06:11:44Z |
|
dc.date.issued |
2014-07 |
|
dc.description.abstract |
American foulbrood (AFB) is a severe brood disease in honeybees. Since sustainable
treatment is not available, selection of genetically resistant honeybee stock is highly desirable. Using a
set of 291 heterozygous microsatellite markers in a bulk segregant analysis with subsequent finemapping
of haploid drone offspring from a single honeybee queen, we identified one significant and three
suggestive quantitative trait loci as well as one significant epistatic interaction influencing prepupal
survival after AFB infection. While we were not able to verify specific genes responsible for tolerance,
we suggest that developmental genes may have played an important role. The identified markers can be
used as regions of interest in future mapping or expression studies. In order to use them for markerassisted
selection in breeding programmes for AFB-resistant honeybee stock, it will be required to
evaluate these loci more extensively under variable experimental conditions. |
en_US |
dc.description.embargo |
2015-07-31 |
|
dc.description.librarian |
hb2014 |
en_US |
dc.description.sponsorship |
European Commission through the 6th framework collaborative Specific Targeted
Research Project BEE SHOP (Bees in Europe and Sustainable Honey Production; EU
contract number: FOOD-CT-2006-022568) and by the German Ministry for Education
and Science (BMBF) through the FUGATO-plus project FUGAPIS (Functional genome
analysis of disease resistance in honeybees, Apis mellifera; project number: 0315125A). |
en_US |
dc.description.uri |
http://link.springer.com/journal/13592 |
en_US |
dc.identifier.citation |
Behrens, D & Moritz, RFA 2014, 'QTL-mapping of individual resistance against American foulbrood in haploid honeybee drone larvae (Apis mellifera)', Apidologie, vol. 45, no. 4, pp. 409-417. |
en_US |
dc.identifier.issn |
0044-8435 (print) |
|
dc.identifier.issn |
1297-9678 (online) |
|
dc.identifier.other |
10.1007/s13592-013-0255-0 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/42179 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Springer |
en_US |
dc.rights |
© INRA, DIB and Springer-Verlag France, 2013.The original publication is available at : http://link.springer.com/journal/13592. |
en_US |
dc.subject |
Paenibacillus larvae |
en_US |
dc.subject |
Invertebrate pathology |
en_US |
dc.subject |
Disease resistance |
en_US |
dc.subject |
Quantitative trait loci (QTL) |
en_US |
dc.subject |
Microsatellites |
en_US |
dc.subject |
American foulbrood (AFB) |
en_US |
dc.title |
QTL-mapping of individual resistance against American foulbrood in haploid honeybee drone larvae (Apis mellifera) |
en_US |
dc.type |
Postprint Article |
en_US |