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Browsing Research Articles (Bioinformatics & Computational Biology Unit) by Issue Date

Now showing items 1-11 of 11

Structural and mechanistic insights into the action of Plasmodium falciparum spermidine synthase

Burger, Pieter Buys; Birkholtz, Lyn-Marie; Joubert, Fourie; Haider, Nashya; Walter, Rolf D.; Louw, Abraham Izak (Elsevier, 2007-02)

Spermidine synthase is currently considered as a promising drug target in the malaria parasite, Plasmodium falciparum, due to the vital role of spermidine in the activation of the eukaryotic translation initiation factor ...
The SeqWord Genome Browser : an online tool for the identification and visualization of atypical regions of bacterial genomes through oligonucleotide usage

Ganesan, Hamilton; Rakitianskaia, A.S. (Anastassia Sergeevna); Davenport, Colin F.; Tummler, Burkhard; Reva, Oleg N. (BioMed Central, 2008-08)

BACKGROUND: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information for large scale sequence analysis and ...
TULIP software and web server : automatic classification of protein sequences based on pairwise comparisons and Z-value statistics

Grando, Delphine; Ortet, Philippe; Joubert, Fourie; Marechal, Eric; Bastien, Olivier (Bentham Science, 2009-03)

A configuration space of homologous protein sequences (or CSHP) has been recently constructed based on pairwise comparisons, with probabilities deduced from Z-value statistics (Monte Carlo methods applied to pairwise ...
Draft genome sequence of Thermoactinomyces sp. strain AS95 isolated from a Sebkha in Thamelaht, Algeria

Bezuidt, Keoagile Ignatius Oliver; Gomri, Mohamed A.; Pierneef, Rian Ewald; Van Goethem, Marc W.; Kharroub, Karima; Cowan, Don A.; Makhalanyane, Thulani Peter (Genomic Standards Consortium, 2016-09-09)

The members of the genus Thermoactinomyces are known for their protein degradative capacities. Thermoactinomyces sp. strain AS95 is a Gram-positive filamentous bacterium, isolated from moderately saline water in the ...
Bacterial profiling of Haemonchus contortus gut microbiome infecting Dohne Merino sheep in South Africa

Mafuna, Thendo; Soma, P.; Tsotetsi‑Khambule, A.M.; Hefer, C.A.; Muchadeyi, F.C.; Thekisoe, O.M.M.; Pierneef, Rian Ewald (Nature Research, 2021-03)

A metagenomic approach was used to study the gut microbiome of Haemonchus contortus feld strains and that of its predilection site, the abomasum of Dohne Merino sheep. The abomasum contents and H. contortus were collected ...
Genetic diversity and population structure analysis reveals the unique genetic composition of South African selected macadamia accessions

Ranketse, Mary; Hefer, Charles A.; Pierneef, Rian Ewald; Fourie, Gerda; Myburg, Alexander Andrew (Springer, 2022-03)

Macadamia nuts are known globally for their high quality and economic value. Global macadamia commercial nut production amounts to 60,000 metric tonnes and is increasing steadily. South Africa is the leading producer with ...
Differences in precipitation regime shape microbial community composition and functional potential in Namib Desert soils

Naidoo, Yashini; Valverde, Angel; Pierneef, Rian Ewald; Cowan, Don A. (Springer, 2022-04)

Precipitation is one of the major constraints influencing the diversity, structure, and activity of soil microbial communities in desert ecosystems. However, the effect of changes in precipitation on soil microbial communities ...
Comparative genomics of Listeria species recovered from meat and food processing facilities

Mafuna, T.; Matle, I.; Magwedere, K.; Pierneef, Rian Ewald; Reva, Oleg N. (American Society for Microbiology, 2022-09-06)

Listeria species (spp.) are contaminants that can survive in food, on equipment, and on food processing premises if appropriate hygiene measures are not used. Homologous stress tolerance genes, virulence gene clusters such ...
Phylogenetic analyses of Salmonella detected along the broiler production chain in Trinidad and Tobago

Khan, Anisa S.; Pierneef, Rian Ewald; Gonzalez-Escalona, Narjol; Maguire, Meghan; Georges, Karla; Abebe, Woubit; Adesiyun, Abiodun Adewale (Elsevier, 2023-02)

This study was conducted to determine the phylogenies of Salmonella strains isolated from cross-sectional studies conducted at hatcheries, broiler farms, processing plants, and retail outlets (broiler production chain) in ...
Whole-genome sequencing of Salmonella serotypes recovered longitudinally from broiler production, processing, and retailing in Trinidad and Tobago

Khan, Anisa S.; Pierneef, Rian Ewald; Abebe, Woubit; Adesiyun, Abiodun Adewale (Springer, 2023-12)

Please read abstract in the article.
Diversity analysis of southern African Artemisia afra using a single nucleotide polymorphism derived from diversity arrays

Sedibe, Moosa Mahmood; Rafiri, Matumelo A.; Dikane, Goitsemang Mahlomola Hendry; Achilonu, Matthew Chilaka; Nkosi, S'busiso Mfan'vele; Ngubane, Xolile Veronica; Pierneef, Rian (Elsevier, 2024-02)

Artemisia afra is an aromatic shrub used as a herbal remedy in southern Africa for various disorders, including coughs, colds, influenza, and, most notably, for the prophylaxis and treatment of Plasmodium falciparum ...

Now showing items 1-11 of 11

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