Browsing Theses and Dissertations (Biochemistry) by Postgraduate "Williams, Marni"

Now showing items 1-2 of 2

Biochemical and structural characterization of novel drug targets regulating polyamine biosynthesis in the human malaria parasite, Plasmodium falciparum

Williams, Marni (University of Pretoria, 2011)

Malaria is prevalent in over 100 countries which is populated by half of the world’s population and culminates in approximately one million deaths per annum, 85% of which occurs in sub-Saharan Africa. The combined resistance ...
Delineation of functional roles of parasite-specific inserts in the malarial S-adenosylmethionine decarboxylase / ornithine decarboxylase

Williams, Marni (University of Pretoria, 2008-08-05)

The polyamines putrescine, spermidine and spermine play essential roles in the proliferation and differentiation of most eukaryotic cells. Inhibition of the polyamine pathway is known to have antitumour and antiparasitic ...

Now showing items 1-2 of 2

Search UPSpace