Browsing Research Articles (Psychiatry) by Author "Roos, J.L. (Johannes Louw)"

Browsing Research Articles (Psychiatry) by Author "Roos, J.L. (Johannes Louw)"

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  • Aberrant function of the C-terminal tail of HIST1H1E accelerates cellular senescence and causes premature aging 
    Flex, Elisabetta; Martinelli, Simone; Van Dijck, Anke; Ciolfi, Andrea; Cecchetti, Serena; Coluzzi, Elisa; Pannone, Luca; Andreoli, Cristina; Radio, Francesca Clementina; Pizzi, Simone; Carpentieri, Giovanna; Bruselles, Allessandro; Catanzaro, Giuseppina; Pedace, Lucia; Miele, Evelina; Carcarino, Elena; Ge, Xiaoyan; Chijiwa, Chieko; Lewis, M.E. Suzanne; Meuwissen, Marije; Kenis, Sandra; Van der Aa, Nathalie; Larson, Austin; Brown, Kathleen; Wasserstein, Melissa P.; Skotko, Brian G.; Begtrup, Amber; Person, Richard; Karayiorgou, Maria; Roos, J.L. (Johannes Louw); Van Gassen, Koen L.; Koopmans, Marije; Bijlsma, Emilia K.; Santen, Gijs W.E.; Barge-Schaapveld, Daniela Q.C.M.; Ruivenkamp, Claudia A.L.; Hoffer, Mariette J.V.; Lalani, Seema R.; Streff, Haley; Craigen, William J.; Graham, Brett H.; Van den Elzen, Annette P.M.; Kamphuis, Daan J.; Ounap, Katrin; Reinson, Karit; Pajusalu, Sander; Wojcik, Monica H.; Viberti, Clara; Di Gaetano, Cornelia; Bertini, Enrico; Petrucci, Simona; De Luca, Alessandro; Rota, Rossella; Ferretti, Elisabetta; Matullo, Giuseppe; Dallapiccola, Bruno; Sgura, Antonella; Walkiewicz, Magdalena; Kooy, R. Frank; Tartaglia, Marco (Elsevier, 2019-09)
    Histones mediate dynamic packaging of nuclear DNA in chromatin, a process that is precisely controlled to guarantee efficient compaction of the genome and proper chromosomal segregation during cell division and to accomplish ...
  • Aetiological doctrines and prevalence of pellagra : 18th century to middle 20th century 
    Viljoen, Margaretha; Bipath, Priyesh; Roos, J.L. (Johannes Louw) (AOSIS, 2018-09-11)
    Pellagra is characterised by dermatological, gastrointestinal and neuropsychiatric manifestations. Millions contracted the disease and hundreds of thousands died between the time it was first recorded until pellagra was ...
  • Afrikaanssprekende emigrante : verliese en verwagtinge 
    Marchetti-Mercer, Maria Chiara; Roos, J.L. (Johannes Louw) (LitNet, 2013-03)
    Die verskynsel van Suid-Afrikaanse emigrasie geniet baie aandag in die media, met die fokus dikwels op sosiopolitieke faktore. Daar word egter min aandag aan die sielkundige ondervindings van diegene wat emigreer, geskenk. ...
  • Afrikaner en skisofrenie : 'n genetiese studie 
    Roos, J.L. (Johannes Louw) (Suid Afrikaanse Akademie vir Wetenskap & Kuns, 2008-06)
    ATKV/SA AKADEMIEPRYS BESTE ARTIKEL 2008. Die artikel gee 'n oorsig oor navorsingbevindings die afgelope tien jaar oor die genetika van skisofrenie in die Afrikaner as 'n stigtersbevolking. Die genealogiese data in die ...
  • Ageism, human rights and ethical aspects of end-of-life care for older people with serious mental illness 
    Kotze, Carla; Roos, J.L. (Johannes Louw) (Frontiers Media S.A., 2022-07-28)
    There are many complex concepts to consider during end-of-life discussions and advance care planning, especially when vulnerable populations such as older individuals with serious mental illness are involved. This article ...
  • Can we close the barn door before the horses get out? A case study of high genetic loading and subsequent development of psychosis 
    Roos, J.L. (Johannes Louw); Lombard, M.; Ladikos, Anastasios (In House Publications, 2011-07)
    No abstract available.
  • Clinical characteristics and premorbid variables in childhood-onset schizophrenia : a descriptive study of twelve cases from a schizophrenia founder population 
    Maydell, R.J.; Van der Walt, C.; Roos, J.L. (Johannes Louw); Scribante, L.; Ladikos, Anastasios (In House Publications, 2009-05)
    OBJECTIVE: To analyze clinical and demographic data of childhood-onset (12 years and younger) schizophrenia patients collected for a genetic study in schizophrenia, undertaken nationally in South Africa, using multiple ...
  • A comparison of two occupational therapy group programs on the functioning of patients with major depressive disorders 
    Ramano, Enos Morankoana; De Beer, Marianne; Roos, J.L. (Johannes Louw); Becker, Piet J. (Edizioni Minerva Medica, 2017-09)
    BACKGROUND ː Occupational therapists, as part of the multi-disciplinary psychiatric team, regularly include activities and or discussion groups to reduce symptoms of patients with major depressive disorders (MDD), and to ...
  • The conceptualisation of "soft skills" among medical students before and after curriculum reform 
    Van Staden, C.W. (Werdie); Joubert, Pierre M.; Pickworth, Glynis Ellen; Roos, J.L. (Johannes Louw); Bergh, Anne-Marie; Kruger, Christa; Schurink, W.J.; Du Preez, Renata; Grey, Somarie V.; Lindeque, B. Gerhard (In House Publications, 2006)
    OBJECTIVE: This paper reports on the conceptualisation of "soft skills" as part of a study carried out among two groups of undergraduate medical students before and after curriculum reform at the School of Medicine of the ...
  • Continuity of care of outpatients with schizophrenia in Pretoria 
    Kotze, A.M.E.; Van Delft, W.F.; Roos, J.L. (Johannes Louw) (Health and Medical Publishing Group, 2010-10)
    OBJECTIVE: To study the needs of outpatients suffering from schizophrenia and their primary caregivers. METHODS: A qualitative descriptive design was selected to study the needs of a non-probability purposive sample of ...
  • Depression later in life : an approach for the family practitioner 
    Roos, J.L. (Johannes Louw) (Medpharm Publications, 2008-05)
    Depressive disorder is the most common mental health problem in older people. Health professionals mainly come into contact with those who are most susceptible to depression, including older people who live in residential ...
  • Dysrhythmogenic potential in acute admissions to psychiatric hospitals and clinics 
    Grant, C.C. (Catharina Cornelia); Steenkamp, B.; Gauche, L.; Becker, Piet J.; Ker, James A.; Roos, J.L. (Johannes Louw); Viljoen, Margaretha (Clinics Cardiv, 2007)
    Co-morbidity between physical disease, especially cardiovascular, and psychological disturbances is well documented. In psychiatric patients, the potential for dysrhythmogenic incidences is increased by the fact that many ...
  • Early deviant behaviour as a dimension trait and endophenotype in schizophrenia 
    Roos, J.L. (Johannes Louw); Kotze, Carla (AOSIS, 2022-04-29)
    BACKGROUND: In psychiatry, there is still a lack of objective biological diagnostic measurements. It is important to investigate measurements or symptom dimensions that can inform diagnostic assessments and allow for a ...
  • End-of-life care in South Africa : important legal developments 
    Kotze, Carla; Roos, J.L. (Johannes Louw) (AOSIS, 2022-01-18)
    All healthcare practitioners should be aware of ethical principles and legislation relevant to end-of-life care. The aim of this scientific letter is to highlight some important South African legal developments that might ...
  • End-of-life decision-making capacity in an elderly patient with schizophrenia and terminal cancer 
    Kotze, Carla; Roos, J.L. (Johannes Louw) (MedPharm Publications, 2020-08-03)
    Medical practitioners are confronted daily with decisions about patients’ capacity to consent to interventions. To address some of the pertinent issues with these assessments, the end-of life decision-making capacity of a ...
  • Family history identifies sporadic schizoaffective disorder as a subtype for genetic studies 
    Van der Merwe, Nicolaas J.; Karayiorgou, Maria; Ehlers, Rene; Roos, J.L. (Johannes Louw) (AOSIS Open Journals, 2020-04)
    BACKGROUND : Schizophrenia is a heterogeneous disorder with strong genetic vulnerability. Family history of schizophrenia has been considered in genetic studies under several models. De novo genetic events seem to play a ...
  • Fine mapping on chromosome 13q32-34 and brain expression analysis implicates MYO16 in schizophrenia 
    Rodriguez-Murillo, Laura; Xu, Bin; Roos, J.L. (Johannes Louw); Abecasis, G.R.; Gogos, Joseph A.; Karayiorgou, Maria (Nature Publishing Group, 2014-03)
    We previously reported linkage of schizophrenia and schizoaffective disorder to 13q32–34 in the European descent Afrikaner population from South Africa. The nature of genetic variation underlying linkage peaks in psychiatric ...
  • Forensic psychiatry in Africa : prospects and challenges 
    Ogunlesi, A.O.; Ogunwale, A.; De Wet, P.H. (Paul Henry); Roos, J.L. (Johannes Louw); Kaliski, S. (In House Publications, 2012-01)
    Forensic Psychiatry has a history that dates back almost two thousand years, and has evolved into a recognised discipline with a robust background of scientific enquiry, mostly because mental health care has always had an ...
  • Genetic and family counselling for schizophrenia : where do we stand now? 
    Roos, J.L. (Johannes Louw) (Health and Medical Publishing Group, 2016-05-06)
    BACKGROUND : Recent genetic findings have led to profound changes in genetic and family counselling for schizophrenia patients and their families. OBJECTIVES : The article gives an overview of the present knowledge ...
  • Genetics of schizophrenia : communicating scientific findings in the clinical setting 
    Roos, J.L. (Johannes Louw) (In House Publications, 2010-06)
    The expected identification of susceptibility genes for psychiatric disorders may bring new opportunities and expectations from patients and families for the clinical translation of research findings in psychiatric genetics. ...