Browsing Research Articles (Psychiatry) by Author "Roos, J.L. (Johannes Louw)"

Browsing Research Articles (Psychiatry) by Author "Roos, J.L. (Johannes Louw)"

Sort by: Order: Results:

  • Handedness in Schizophrenia and schizoaffective disorder in an Afrikaner founder population 
    Mataboge, R.H.; Joubert, Marinda; Jordaan, J.C. (Joyce); Reynecke, Fransonet; Roos, J.L. (Johannes Louw) (In House Publications, 2014-01)
    OBJECTIVE : An association between the Leucine-rich repeat trans membrane neuronal 1 gene (LRRTM1), schizophrenia/schizoaffective disorder and handedness was recently claimed to be established. This study aimed to test ...
  • Homicide–suicide : practical implications for risk reduction and support services at primary care level 
    Kotze, Carla; Roos, J.L. (Johannes Louw) (Medpharm Publications, NISC (Pty) and Cogent, Taylor and Francis Group, 2019)
    Homicide–suicide (HS) has been defined as homicide committed by a person who subsequently commits suicide within one week of the homicide. In most cases it occurs within 24 hours. HS is a public health problem, victimising ...
  • Loss-of-function variants in schizophrenia risk and SETD1A as a candidate susceptibility gene 
    Takata, Atsushi; Xu, Bin; Ionita-Laza, Iuliana; Roos, J.L. (Johannes Louw); Gogos, Joseph A.; Karayiorgou, Maria (Elsevier, 2014-05)
    Loss-of-function (LOF) (i.e., nonsense, splice site, and frameshift) variants that lead to disruption of gene function are likely to contribute to the etiology of neuropsychiatric disorders. Here, we perform a systematic ...
  • Medical students on the value of role models for developing ‘soft skills’ - “That’s the way you do it” 
    Joubert, Pierre M.; Kruger, Christa; Bergh, Anne-Marie; Pickworth, Glynis Ellen; Van Staden, C.W. (Werdie); Roos, J.L. (Johannes Louw); Schurink, W.J.; Du Preez, Renata; Grey, Somarie V.; Lindeque, B. Gerhard (In House Publications, 2006)
    OBJECTIVE: The Soft Skills Project examined the professional development of medical students at the University of Pretoria, especially their doctor-patient interaction skills and professional socialisation. This paper ...
  • Medical students’ perceptions of their development of ‘soft skills’ Part I : a qualitative research methodology 
    Schurink, W.J.; Kruger, Christa; Bergh, Anne-Marie; Van Staden, C.W. (Werdie); Roos, J.L. (Johannes Louw); Pickworth, Glynis Ellen; Joubert, Pierre M.; Du Preez, Renata; Grey, Somarie V.; Lindeque, B. Gerhard (South African Academy of Family Practice, 2006)
    BACKGROUND: Following the introduction of a new, integrated, problem-oriented undergraduate medical curriculum at the University of Pretoria (UP) in 1997, a research project was undertaken to study interpersonal skills, ...
  • Medical students’ perceptions of their development of ‘soft skills’ Part II : The development of ‘soft skills’ through ‘guiding and growing’ 
    Bergh, Anne-Marie; Van Staden, C.W. (Werdie); Joubert, Pierre M.; Kruger, Christa; Pickworth, Glynis Ellen; Roos, J.L. (Johannes Louw); Schurink, W.J.; Du Preez, Renata; Grey, Somarie V.; Lindeque, B. Gerhard (South African Academy of Family Practice, 2006)
    BACKGROUND: This paper reports on medical students’ views on the ways in which their ‘soft skills’ were developed. It is the result of a study on soft skills among two groups of students before and after curriculum reform ...
  • Meta-analysis of 32 genome-wide linkage studies of schizophrenia 
    Ng, M.Y.M.; Levinson, D.F.; Faraone, S.V.; Suarez, B.K.; DeLisi, L.E.; Arinami, T.; Riley, B.; Paunio, T.; Pulver, A.E.; Irmansya; Holmans, P.A.; Escamilla, M.; Wildenauer, D.B.; Williams, Neal M.; Laurent, Claude; Mowry, B.J.; Brzustowicz, L.M.; Maziade, M.; Sklar, P.; Garver, D.L.; Abecasis, G.R.; Lerer, B.; Fallin, M.D.; Gurling, H.M.D.; Gejman, P.V.; Lindholm, E.; Moises, H.W.; Byerley, W.; Wijsman, E.M.; Foraboso, P.; Tsuang, M.T.; Hwu, H-G.; Okazaki, Y.; Kendler, K.S.; Wormley, B.; Fanous, A.; Walsh, D.; O'Neill, F.A.; Peltonen, L.; Nestadt, G.; Lasseter, V.K.; Liang, K.Y.; Papadimitriou, G.M.; Dikeos, D.G.; Schwab, S.G.; Owen, M.J.; O'Donovan, M.C.; Norton, N.; Hare, E.; Raventos, H.; Nicolini, H.; Albus, M.; Maier, W.; Nimgaonkar, V.L.; Terenius, L.; Mallet, J.; Jay, M.; Godard, S.; Nertney, D.; Alexander, M.; Crowe, R.R.; Silverman, J.M.; Basset, A.S.; Roy, M-A.; Merette, C.; Pato, C.N.; Pato, M.T.; Roos, J.L. (Johannes Louw); Kohn, Y.; Amann-Zalcenstein, D.; Kalsi, G.; McQuillin, A.; Curtis, D.; Brynjolfson, J.; Sigmundsson, T.; Petursson, H.; Sanders, A.R.; Duan, J.; Jazin, E.; Myles-Worsley, M.; Karayiorgou, Maria; Lewis, C.M. (Nature Publishing Group, 2009-08)
    A genome scan meta-analysis (GSMA) was carried out on 32 independent genome-wide linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with schizophrenia SCZ) or related disorders. The primary ...
  • Methodological limitations to a study on interpersonal therapy 
    Roos, J.L. (Johannes Louw); Kruger, Christa; Bohmer, M.W. (Manfred) (Health and Medical Publishing Group, 2013-06)
    Studies comparing pharmaco- v. psychotherapy in HIV-positive patients with depression are of great importance. These are vulnerable patients, both in a psychological sense and because of potential drug interactions. ...
  • The neurobiological basis of fear : a concise review 
    Panzer, Annie; Viljoen, Margaretha; Roos, J.L. (Johannes Louw) (In House Publications, 2007-05)
    Anxiety disorders are amongst the most common psychiatric disorders affecting approximately 25% of all adults. Fear and anxiety have many shared neuroanatomical and neurochemical characteristics. In this paper we ...
  • Nuwe bevindings oor die genetiese argitektuur van skisofrenie : die bydrae van studies onder Afrikaners 
    Roos, J.L. (Johannes Louw) (AOSIS Open Journals, 2014-02-24)
    Die genetiese komponent in die etiologie van skisofrenie word reeds ’n geruime tyd al aanvaar. Die onderliggende argitektuur van die genetiese risiko bly ’n punt van bespreking. Vroeë studies oor koppeling en ...
  • Phenotypic features of patients with schizophrenia carrying de novo gene mutations : a pilot study 
    Malherbe, P.J.; Roos, J.L. Jr.; Ehlers, Rene; Karayiorgou, Maria; Roos, J.L. (Johannes Louw) (Elsevier, 2015-01)
    Genome-wide scans have revealed a significant role for de novo copy number variants (CNVs) and Single Nucleotide variants (SNVs) in the genetic architecture of schizophrenia. The present study attempts to parse schizophrenia ...
  • Profile of mortality of patients admitted to Weskoppies Psychiatric Hospital in South Africa over a 5-year period (2001-2005) 
    Khamker, Nadira; Moola, N.M.; Roos, J.L. (Johannes Louw); Rheeder, Paul (In House Publications, 2010-07)
    OBJECTIVE: Mortality in the psychiatric population, both from natural and unnatural causes, is higher than in the general population and this is despite an improvement in the delivery of care and treatment of mental illness ...
  • Psychiatric and other contributing factors in homicide-suicide cases, from northern Gauteng, South Africa over a six-year period 
    Kotze, Carla; Khamker, Nadira; Lippi, Gian; Naidu, Kalai; Pooe, J. Mosidi; Sokudela, Funeka Brenda; Roos, J.L. (Johannes Louw) (Routledge, 2018-01)
    Homicide committed by a person who subsequently commits suicide within one week of the homicide is a relatively rare event. The current study used an explanatory sequential design, including psychological autopsies, to ...
  • Scan statistic-based analysis of exome sequencing data identifies FAN1 at 15q13.3 as a susceptibility gene for schizophrenia and autism 
    Ionita-Laza, Iuliana; Xu, Bin; Makarov, Vlad; Buxbaum, Joseph D.; Roos, J.L. (Johannes Louw); Gogos, Joseph A.; Karayiorgou, Maria (National Academy of Sciences, 2014-01)
    We used a family-based cluster detection approach designed to localize significant rare disease–risk variants clusters within a region of interest to systematically search for schizophrenia (SCZ) susceptibility genes ...
  • Sub-specialties in psychiatry : towards parity in mental health training and services 
    Stein, D.J. (Dan); Betancourt, O. Alonso; Emsley, Robin A.; Jeenah, Yasmien; Mkize, Dan; Pretorius, Janus; Rataemane, Solomon; Roos, J.L. (Johannes Louw); Szabo, Christopher P. (Health and Medical Publishing Group, 2009-01)
    Neuropsychiatric disorders account for 5 of the 10 most disabling medical disorders worldwide, and for a particularly large component of the burden of disease in South Africa. Unfortunately, as elsewhere, training and ...
  • Suicide risk in schizophrenia - a follow-up study after 20 years. Part 1 : outcome and associated social factors 
    Lippi, Gian; Smit, D.J.; Jordaan, J.C. (Joyce); Roos, J.L. (Johannes Louw) (Health and Medical Publishing Group, 2009-10)
    OBJECTIVE: This study re-evaluated, after a period of 20 years, a cohort of patients with schizophrenia who had been considered to be at high risk for suicide. The outcome and social factors associated with their suicide ...
  • Suicide risk in schizophrenia - a follow-up study after 20 years. Part 2 : symptomatology and pharmacotherapy 
    Lippi, Gian; Smit, D.J.; Jordaan, J.C. (Joyce); Roos, J.L. (Johannes Louw) (Health and Medical Publishing Group, 2009-12)
    OBJECTIVE: This study followed up, after a period of 20 years, a group of patients with schizophrenia who were considered to be at high risk for suicide. In Part 1 we reported on outcome and associated social factors, and ...
  • Testing the effectiveness of existing psycho-educational material (The Alliance Programme) for patients suffering from schizophrenia in the South African context 
    Pooe, J.M.; Sokudela, Funeka Brenda; Roos, J.L. (Johannes Louw); Motlana, L.M.; Dlamini, N.; Snyman, M.E. (Martha Elizabeth) (In House Publications, 2010-09)
    OBJECTIVE: The objective of this study was to test the effectiveness of the existing psycho-educational material (The Alliance Programme) for patients suffering from schizophrenia in the South African context. METHOD: A ...
  • Training undergraduate medical students in ‘soft skills’ – a qualitative research project at the University of Pretoria 
    Kruger, Christa; Schurink, W.J.; Bergh, Anne-Marie; Joubert, Pierre M.; Roos, J.L. (Johannes Louw); Van Staden, C.W. (Werdie); Pickworth, Glynis Ellen; Du Preez, Renata; Grey, Somarie V.; Lindeque, B. Gerhard (In House Publications, 2006)
    No abstract available.
  • Unipolar mania reconsidered evidence from a South African study 
    Grobler, Christoffel; Roos, J.L. (Johannes Louw); Bekker, P. (Clinical & Medical Journals, 2014-01)
    OBJECTIVE : There is a lack of studies that examine prevalence and phenomenology of bipolar disorder in Africa. In literature, a unipolar manic course of illness in particular is reported to be rare. The purpose of this ...