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dc.contributor.author | Fourie, Niel | |
dc.contributor.author | Erasmus, G.L. | |
dc.contributor.author | Schultz, R.A. (Rowena Anitra) | |
dc.contributor.editor | Verwoerd, Daniel Wynand | |
dc.contributor.upauthor | Prozesky, Leon | |
dc.date.accessioned | 2013-09-12T08:41:28Z | |
dc.date.available | 2013-09-12T08:41:28Z | |
dc.date.created | 2013 | |
dc.date.issued | 1995 | |
dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en |
dc.description.abstract | Gousiekte was induced in sheep and goats by the oral and intravenous (i/v) administration of methanolic and ethanolic precipitates of aqueous extracts of Pavetta harborii. Further purification of the toxic principle was carried out by dialysis and ion-exchange chromatography. The toxin was eluted from the cation-exchange resin with 1 mol/l of ammonium acetate and finally purified on Sephadex G-10 and silica gel. Spots on thin-layer chromatographic plates (TLC) were visualized with ninhydrin. Gousiekte was induced with the pure toxin after i/v administration in goats. The yield of pure toxin was about 10 mg/kg of dried leaves. A compound, indistinguishable from the above on TLC, was also isolated from the gousiekte-inducing plants Pavetta schumanniana, Fadogia homblei and Pachystigma pygmaeum. | en |
dc.description.librarian | mn2013 | |
dc.identifier.citation | Fourie, N, Erasmus, GL, Schultz, RA & Prozesky, L 1995, 'Isolation of the toxin responsible for gousiekte, a plant-induced cardiomyopathy of ruminants in southern Africa’. Onderstepoort Journal of Veterinary Research, vol. 62, no. 2, pp. 77-87. | en |
dc.identifier.issn | 0330-2465 | |
dc.identifier.uri | http://hdl.handle.net/2263/31699 | |
dc.language.iso | en | en |
dc.publisher | Published by the Agricultural Research Council, Onderstepoort Veterinary Institute | en |
dc.rights | © ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital). | en |
dc.subject | Veterinary medicine | en |
dc.subject | Gousiekte | en |
dc.subject | Cardiomyopathy | en |
dc.subject | Cardiac failure | en |
dc.subject | Plant poisoning | en |
dc.subject | Cardiotoxin | en |
dc.subject.lcsh | Veterinary medicine -- South Africa | |
dc.title | Isolation of the toxin responsible for gousiekte, a plant-induced cardiomyopathy of ruminants in southern Africa | en |
dc.type | Article | en |