dc.contributor.author |
Odendaal, M.W.
|
|
dc.contributor.author |
Morris, S.
|
|
dc.contributor.author |
Du Preez, E.
|
|
dc.contributor.author |
Aitchison, Henry
|
|
dc.contributor.editor |
Verwoerd, Daniel Wynand |
|
dc.date.accessioned |
2012-12-12T08:50:56Z |
|
dc.date.available |
2012-12-12T08:50:56Z |
|
dc.date.created |
2012 |
|
dc.date.issued |
1997 |
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dc.description |
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. |
en_US |
dc.description.abstract |
A multivalent vaccine consisting of inactivated bovine herpes virus-1 (BHV-1 ). also known as infectious bovine rhinotracheitis virus (IBR) , para-influenza type-3 virus (PIȝ) and the leukotoxin of Pasteurella haemolytica A 1, were combined with the addition of aluminium hydroxide as adjuvant, and administered to post-weaned calves, and the serum tested for seroconversion to each antigen. Two groups of calves (n = 150 and n = 68) were used and were randomly divided into three subgroups. The first group of 150 calves were immunized with the multivalent vaccine (three batches) to test its first-stage stability (vaccine 3 months old) and the second group were immunized with the same vaccine 1 year later, in order to test its immunogenicity. A significant increase in titres occurred after the day 0 and 28 immunizations, for each of the three antigens in the multivalent vaccine, as measured on days 0 and 42. lmmunoconversion occurred after immunization with the 3-month- and 1-year-old vaccine. The immunogenic stability of antigens in the vaccine was demonstrated after a 1-year period when the vaccine was kept at 4-6 °C. |
en_US |
dc.identifier.citation |
Odendaal, MW, Morris, S, Du Preez, E & Aitchison, H 1997, 'The humoral immune response in cattle after immunization with a multivalent IBR/PI 3/ Pasteurella haemolytica A1 leukotoxin vaccine’. Onderstepoort Journal of Veterinary Research, vol. 64, no. 3, pp. 205-212. |
en_US |
dc.identifier.issn |
0330-2465 |
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dc.identifier.uri |
http://hdl.handle.net/2263/20746 |
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dc.language.iso |
en |
en_US |
dc.publisher |
Published by the Agricultural Research Council, Onderstepoort Veterinary Institute |
en_US |
dc.rights |
© ARC-Onderstepoort (original).
© University of Pretoria. Dept of Library Services (digital). |
en_US |
dc.subject |
Veterinary medicine |
en_US |
dc.subject |
BHV-1 |
en_US |
dc.subject |
Bovine herpes virus-1 |
en_US |
dc.subject |
Cattle |
en_US |
dc.subject |
IBR |
en_US |
dc.subject |
Immunoconversion |
en_US |
dc.subject |
Immunogenicity |
en_US |
dc.subject |
Infectious bovine tracheitis |
en_US |
dc.subject |
Multivalent vaccine |
en_US |
dc.subject |
Para-influenza |
en_US |
dc.subject |
Pasteurella haemolytica |
en_US |
dc.subject |
PIȝ |
en_US |
dc.subject.lcsh |
Veterinary medicine -- South Africa |
|
dc.title |
The humoral immune response in cattle after immunization with a multivalent IBR/PI 3/ Pasteurella haemolytica A1 leukotoxin vaccine |
en_US |
dc.type |
Article |
en_US |