A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy

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dc.contributor.author Hocepied, A.M.
dc.contributor.author Westerink, H.
dc.contributor.author Lakier, R.
dc.date.accessioned 2012-11-28T10:04:27Z
dc.date.available 2012-11-28T10:04:27Z
dc.date.issued 2012
dc.description.abstract The Department of Radiation Oncology at the previously named Pretoria Academic Hospital (now the Steve Biko Hospital) undertook a pilot study between 2000 and 2001 of 20 patients who were human immunodeficiency virus-positive with locally advanced cancer of the cervix. At the time of the study, these patients were not on antiretroviral therapy, as per government policy. The patients were randomised into two arms. Six patients underwent a short palliative course of radiotherapy and 13 received a protracted and radical course of radiotherapy. One patient was lost to follow-up. Although the results were not statistically significant, the short course of palliative radiotherapy was adequate in terms of toxicity. As expected, the radical course was associated with a greater and more significant toxicity, because of the suppressed immune status of the participants. en_US
dc.description.uri http://www.sajgo.co.za/index.php/sajgo en_US
dc.identifier.citation Hocepied, AM, Westerink, H & Lakier, R 2012, 'A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy', Southern African Journal of Gynaecological Oncology, vol. 4, no. 2, pp. 55-58. en_US
dc.identifier.issn 2074-2835
dc.identifier.uri http://hdl.handle.net/2263/20581
dc.language.iso en en_US
dc.publisher Open Journals Systems en_US
dc.rights © SASGO en_US
dc.subject HIV en_US
dc.subject Radiotherapy en_US
dc.subject Locally advanced cervical cancer en_US
dc.subject.lcsh Cervix uteri -- Cancer -- Treatment en
dc.subject.lcsh HIV-positive women -- Diseases -- Radiotherapy en
dc.title A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy en_US
dc.type Article en_US


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