A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy

dc.contributor.authorHocepied, A.M. (Alain)
dc.contributor.authorWesterink, H.
dc.contributor.authorLakier, Roy
dc.date.accessioned2012-11-28T10:04:27Z
dc.date.available2012-11-28T10:04:27Z
dc.date.issued2012
dc.description.abstractThe Department of Radiation Oncology at the previously named Pretoria Academic Hospital (now the Steve Biko Hospital) undertook a pilot study between 2000 and 2001 of 20 patients who were human immunodeficiency virus-positive with locally advanced cancer of the cervix. At the time of the study, these patients were not on antiretroviral therapy, as per government policy. The patients were randomised into two arms. Six patients underwent a short palliative course of radiotherapy and 13 received a protracted and radical course of radiotherapy. One patient was lost to follow-up. Although the results were not statistically significant, the short course of palliative radiotherapy was adequate in terms of toxicity. As expected, the radical course was associated with a greater and more significant toxicity, because of the suppressed immune status of the participants.en_US
dc.description.urihttp://www.sajgo.co.za/index.php/sajgoen_US
dc.identifier.citationHocepied, AM, Westerink, H & Lakier, R 2012, 'A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy', Southern African Journal of Gynaecological Oncology, vol. 4, no. 2, pp. 55-58.en_US
dc.identifier.issn2074-2835
dc.identifier.urihttp://hdl.handle.net/2263/20581
dc.language.isoenen_US
dc.publisherOpen Journals Systemsen_US
dc.rights© SASGOen_US
dc.subjectHIVen_US
dc.subjectRadiotherapyen_US
dc.subjectLocally advanced cervical canceren_US
dc.subject.lcshCervix uteri -- Cancer -- Treatmenten
dc.subject.lcshHIV-positive women -- Diseases -- Radiotherapyen
dc.titleA pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapyen_US
dc.typeArticleen_US

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