The treatment of cholesterol : safety and efficacy of statin therapy

Ker, James A.

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dc.contributor.author	Ker, James A.
dc.date.accessioned	2012-11-28T10:02:54Z
dc.date.available	2012-11-28T10:02:54Z
dc.date.issued	2012-10
dc.description.abstract	Statins are the most widely prescribed class of drugs worldwide, and also the most powerful cholesterol-lowering drugs currently available. Statins inhibit 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG CoA) reductase, which leads to reduced cholesterol synthesis. In addition, low-density cholesterol receptors on the hepatocyte surface are upregulated, leading to increased clearance of cholesterol. Cholesterol levels are reduced, which leads to a significant reduction in cardiovascular events, of 25-45%.	en_US
dc.description.uri	http://www.sapj.co.za/index.php/SAPJ	en_US
dc.identifier.citation	Ker, J 2012, 'The treatment of cholesterol : safety and efficacy of statin therapy', SA Pharmaceutical Journal, vol. 79, no. 9, pp. 27-28.	en_US
dc.identifier.issn	1015-1362
dc.identifier.uri	http://hdl.handle.net/2263/20580
dc.language.iso	en	en_US
dc.publisher	Medpharm Publications	en_US
dc.rights	© Medpharm	en_US
dc.subject	Cholesterol	en_US
dc.subject	Statin therapy	en_US
dc.subject.lcsh	Cholesterol -- Treatment	en
dc.title	The treatment of cholesterol : safety and efficacy of statin therapy	en_US
dc.type	Article	en_US