The treatment of cholesterol : safety and efficacy of statin therapy
| dc.contributor.author | Ker, James A. | |
| dc.contributor.email | james.ker@up.ac.za | en_US |
| dc.date.accessioned | 2012-11-28T10:02:54Z | |
| dc.date.available | 2012-11-28T10:02:54Z | |
| dc.date.issued | 2012-10 | |
| dc.description.abstract | Statins are the most widely prescribed class of drugs worldwide, and also the most powerful cholesterol-lowering drugs currently available. Statins inhibit 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG CoA) reductase, which leads to reduced cholesterol synthesis. In addition, low-density cholesterol receptors on the hepatocyte surface are upregulated, leading to increased clearance of cholesterol. Cholesterol levels are reduced, which leads to a significant reduction in cardiovascular events, of 25-45%. | en_US |
| dc.description.uri | http://www.sapj.co.za/index.php/SAPJ | en_US |
| dc.identifier.citation | Ker, J 2012, 'The treatment of cholesterol : safety and efficacy of statin therapy', SA Pharmaceutical Journal, vol. 79, no. 9, pp. 27-28. | en_US |
| dc.identifier.issn | 1015-1362 | |
| dc.identifier.uri | http://hdl.handle.net/2263/20580 | |
| dc.language.iso | en | en_US |
| dc.publisher | Medpharm Publications | en_US |
| dc.rights | © Medpharm | en_US |
| dc.subject | Cholesterol | en_US |
| dc.subject | Statin therapy | en_US |
| dc.subject.lcsh | Cholesterol -- Treatment | en |
| dc.title | The treatment of cholesterol : safety and efficacy of statin therapy | en_US |
| dc.type | Article | en_US |