dc.contributor.author |
Ker, James A.
|
|
dc.date.accessioned |
2012-05-23T08:27:06Z |
|
dc.date.available |
2012-05-23T08:27:06Z |
|
dc.date.issued |
2011-09-06 |
|
dc.description.abstract |
INTRODUCTION: An increased cardiovascular mortality has been described in patients with spondyloarthropathies
due to HLA-B27. Numerous cardiovascular afflictions are currently known to be associated with HLA-B27. These
include aortic root dilation, aortic regurgitation, mitral regurgitation, myocarditis, heart failure, pericarditis, pericardial
effusion, atrioventricular conduction block and more recently, the presence of J-waves.
MATERIALS AND METHODS: 48 HLA-B27 positive patients (23 men and 25 women) were included in this observational
study. A 12-lead electrocardiogram and a signal-averaged electrocardiogram was recorded in every patient in order to
detect any possible J-waves and ventricular late potentials respectively.
RESULTS: 27 out of these 48 patients demonstrated a visible J-wave in the inferolateral leads. It was revealed that
there is a likelihood ratio of 11.386 (p=0.00074) to demonstrate a visible J-wave if the duration of low-amplitude signals
is less than 30 ms.
CONCLUSION: HLA-B27 positive patients has a high incidence of inferolateral cardiac J-waves. There is a high
probability of demonstrating such a J-wave on the 12-lead electrocardiogram if the duration of ventricular late potentials
is less than 30 ms. The possible mechanisms of this electrocardiographic paradox is discussed. |
en_US |
dc.description.uri |
http://www.la-press.com |
en_US |
dc.identifier.citation |
Ker J (2011) HLA-B27 and an Electrocardiographic Peculiarity. J Clinic Experiment Cardiol 2:149. DOI: 10.4172/2155-9880.1000149 |
en_US |
dc.identifier.issn |
1179-5468 |
|
dc.identifier.other |
10.4172/2155-9880.1000149 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/18832 |
|
dc.language.iso |
en |
en_US |
dc.rights |
© 2011 Ker J. This is an open-access article distributed under the
terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original author and
source are credited. |
en_US |
dc.subject |
HLA-B27 |
en_US |
dc.subject |
Ventricular |
en_US |
dc.subject |
Late potentials |
en_US |
dc.subject |
J-wave |
en_US |
dc.title |
HLA-B27 and an electrocardiographic peculiarity |
en_US |
dc.type |
Article |
en_US |