Browsing Research Articles (Surgery) by Subject "Low- and middle-income countries (LMICs)"

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Alternative splicing events and their clinical significance in colorectal cancer : targeted therapeutic opportunities

Manabile, Mosebo Armstrong; Hull, Rodney; Khanyile, Richard; Molefi, Thulo; Damane, Botle Precious; Mongan, Nigel Patrick; Bates, David Owen Bates; Dlamini, Zodwa (MDPI, 2023-08-07)

Colorectal cancer (CRC) ranks as one of the top causes of cancer mortality worldwide and its incidence is on the rise, particularly in low-middle-income countries (LMICs). There are several factors that contribute to the ...
Microbiomes, epigenomics, immune response, and splicing signatures interplay : potential use of combination of regulatory pathways as targets for malignant mesothelioma

Setlai, Botle Precious; Mkhize-Kwitshana, Zilungile Lynette; Mehrotra, Ravi; Mulaudzi, Thanyani Victor; Dlamini, Zodwa (MDPI, 2022-08-12)

Malignant mesotheliomas (MM) are hard to treat malignancies with poor prognosis and high mortality rates. This cancer is highly misdiagnosed in Sub-Saharan African countries. According to literature, the incidence of MM ...

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