Browsing Research Articles (Surgery) by Subject "Inflammasome"

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Influence of the microbiome metagenomics and epigenomics on gastric cancer

Mathebela, Precious; Damane, Botle Precious; Mulaudzi, Thanyani Victor; Mkhize-Khwitshana, Zilungile Lynette; Gaudji, Guy Roger; Dlamini, Zodwa (MDPI, 2022-11)

Gastric cancer (GC) is one of the major causes of cancer deaths worldwide. The disease is seldomly detected early and this limits treatment options. Because of its heterogeneous and complex nature, the disease remains ...
Unraveling the complex interconnection between specific Inflammatory signaling pathways and mechanisms involved in HIV-associated colorectal oncogenesis

Damane, Botle Precious; Mulaudzi, Thanyani Victor; Kader, Sayed Shakeel; Naidoo, Pragalathan; Savkovic, Suzana D.; Dlamini, Zodwa; Mkhize-Kwitshana, Zilungile Lynette (MDPI, 2023-02)

The advancement of HIV treatment has led to increased life expectancy. However, people living with HIV (PLWH) are at a higher risk of developing colorectal cancers. Chronic inflammation has a key role in oncogenesis, ...

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