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Browsing Research Articles (Paraclinical Sciences) by Author "Choonara, Yahya E."

Now showing items 1-4 of 4

Chemotherapeutic efficacy of implantable antineoplastic-treatment protocols in an optimal mouse model for human ovarian carcinoma cell targeting

Pantshwa, Jonathan M.; Rhoda, Khadija; Clift, Sarah Jane; Pradeep, Priyamvada; Choonara, Yahya E.; Kumar, Pradeep; Du Toit, Lisa C.; Penny, Clement; Pillay, Viness; Pillay, Viness (MDPI Publishing, 2018-10-04)

The present study aimed to design and develop a nanocomposite drug delivery system employing an antineoplastic-loaded antibody functionalized nanomicelle encapsulated within a Chitosan–Poly(vinylpyrrolidone)–Poly(N-iso ...
Ex vivo and In vivo characterization of interpolymeric blend/nanoenabled gastroretentive levodopa delivery systems

Ngwuluka, Ndidi C.; Choonara, Yahya E.; Modi, Girish; Du Toit, Lisa C.; Kumar, Pradeep; Meyer, Leith Carl Rodney; Snyman, Tracy; Pillay, Viness (Hindawi Publishing, 2017)

One approach for delivery of narrow absorption window drugs is to formulate gastroretentive drug delivery systems. This study was undertaken to provide insight into in vivo performances of two gastroretentive systems (PXLNET ...
In vitro and in vivo evaluation of an oral multi-layered multi-disk tablet for specialized chronotherapeutic drug delivery

Khan, Zaheeda; Govender, Mershen; Indermun, Sunaina; Kumar, Pradeep; Choonara, Yahya E.; Du Toit, Lisa C.; Meyer, Leith Carl Rodney; Pillay, Viness (Elsevier, 2018-06)

Chronotherapeutic disorders such as hypertension, cardiovascular disease and asthma commonly involve the use of controlled zero-order release formulations. Ideally, the required drug should be released at predetermined ...
In vivo evaluation of an Ultra-fast Disintegrating Wafer matrix : a molecular simulation approach to the ora-mucoadhesivity

Reddy, Deshika; Choonara, Yahya E.; Kumar, Pradeep; Govender, Mershen; Indermun, Sunaina; Du Toit, Lisa C.; Meyer, Leith Carl Rodney; Pillay, Viness (Elsevier, 2017-02)

The purpose of this study was to design and evaluate the performance of an Ultra-fast Disintegrating Wafer (U-D-WAF) loaded with highly water soluble diphenhydramine hydrochloride (DPH) through the oramucosa of the Large ...

Now showing items 1-4 of 4

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Browsing Research Articles (Paraclinical Sciences) by Author "Choonara, Yahya E."

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