Browsing Paraclinical Sciences by UP Author "Crafford, Jan Ernst"

Browsing Paraclinical Sciences by UP Author "Crafford, Jan Ernst"

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  • Epoxyscillirosidine induced cytotoxicity and ultrastructural changes in a rat embryonic cardiomyocyte (H9c2) cell line 
    Isa, Hamza Ibrahim; Ferreira, Gezina Catharina Helena; Crafford, Jan Ernst; Botha, C.J. (Christoffel Jacobus) (MDPI, 2019-05)
    Moraea pallida Bak. (yellow tulp) poisoning is the most important cardiac glycoside-induced intoxication in ruminants in South Africa. The toxic principle, 1α, 2α-epoxyscillirosidine, is a bufadienolide. To replace the use ...
  • Evaluation of in vitro neutralization of epoxyscillirosidine by antibodies raised in sheep 
    Isa, Hamza Ibrahim; Ferreira, Gezina Catharina Helena; Crafford, Jan Ernst; Botha, C.J. (Christoffel Jacobus) (Elsevier, 2019-06)
    Intoxication by Moraea pallida Bak. (yellow tulp) in livestock is of great importance in South Africa, ranking top among all plant-induced cardiac glycoside toxicosis. The toxic principle, a bufadienolide, is 1α, ...
  • A potential krimpsiekte vaccine 
    Botha, C.J. (Christoffel Jacobus); Crafford, Jan Ernst; Butler, V.P. Jr.; Stojanovic, M.N.; Labuschagne, Leonie (Agricultural Research Council, ARC-OVI and the University of Pretoria, 2007-12)
    Krimpsiekte, a chronic form of cardiac glycoside poisoning, is an important plant-induced intoxication of small stock in South Africa. It is caused by cumulative, neurotoxic bufadienolides, such as cotyledoside. A ...
  • Raising antibodies against epoxyscillirosidine, the toxic principle contained in Moraea pallida Bak. (Iridaceae), in rabbits 
    Isa, Hamza Ibrahim; Ferreira, Gezina Catharina Helena; Crafford, Jan Ernst; Botha, C.J. (Christoffel Jacobus) (Elsevier, 2019-11)
    Moraea pallida Bak. (yellow tulp) poisoning is the most important plant cardiac glycoside toxicosis in South Africa. The toxic principle, a bufadienolide, is 1α, 2α-epoxyscillirosidine. The aim was to investigate the ...