Browsing Paraclinical Sciences by UP Author "Aro, Abimbola Obemisola"

Now showing items 1-11 of 11

Antibacterial activity and mode of action of acetone crude leaf extracts of underinvestigated Syzygium and Eugenia (Myrtaceae) species on multidrug resistant porcine diarrhoeagenic Escherichia coli

Famuyide, Ibukun Michael; Aro, Abimbola Obemisola; Fasina, Folorunso Oludayo; Eloff, Jacobus Nicolaas; McGaw, Lyndy Joy (BioMed Central, 2019-05-22)

BACKGROUND : Diarrhoea, a global economically important disease burden affecting swine and, especially piglets, is commonly caused by infection with entero-toxigenic E. coli (ETEC). Adherence of ETEC to porcine ...
Antibacterial and antibiofilm activity of acetone leaf extracts of nine underinvestigated south African Eugenia and Syzygium (Myrtaceae) species and their selectivity indices

Famuyide, Ibukun Michael; Aro, Abimbola Obemisola; Fasina, Folorunso Oludayo; Eloff, Jacobus Nicolaas; McGaw, Lyndy Joy (BioMed Central, 2019-06-20)

BACKGROUND : Antimicrobial resistance (AMR) remains an important global health issue but the gap between AMR and development of new antimicrobials is increasing. Plant extracts may have good activity per se or may be ...
Benzofuran–appended 4-aminoquinazoline hybrids as epidermal growth factor receptor tyrosine kinase inhibitors: synthesis, biological evaluation and molecular docking studies

Mphahlele, Malose J.; Maluleka, Marole M.; Aro, Abimbola Obemisola; McGaw, Lyndy Joy; Choong, Yee Siew (Informa Healthcare, 2018)

A series of 2-arylbenzo[b]furan–appended 4-aminoquinazoline hybrids were prepared and evaluated for cytotoxicity in vitro against the human lung cancer (A549), colorectal adenocarcinoma (Caco-2), hepatocellular carcinoma ...
Extracts of six Rubiaceae species combined with rifampicin have good in vitro synergistic antimycobacterial activity and good anti-inflammatory and antioxidant activities

Aro, Abimbola Obemisola; Dzoyem, Jean Paul; Eloff, Jacobus Nicolaas; McGaw, Lyndy Joy (BioMed Central, 2016-10-03)

BACKGROUND : The Rubiaceae family has played a significant role in drug discovery by providing molecules with potential use as templates for the development of therapeutic drugs. This study was designed to study the ...
Flavonoids isolated from the South African weed Chromolaena odorata (Asteraceae) have pharmacological activity against uropathogens

Omokhua-Uyi, Aitebiremen Gift; Abdalla, Muna Ali; Leonard, Carmen M.; Aro, Abimbola Obemisola; Uyi, Osariyekemwen O.; Van Staden, Johannes; McGaw, Lyndy Joy (BioMed Central, 2020-07)

BACKGROUND: Urinary tract infections (UTIs) caused by opportunistic pathogens are among the leading health challenges globally. Most available treatment options are failing as a result of antibiotic resistance and ...
Fractions and isolated compounds from oxyanthus speciosus subsp. stenocarpus (Rubiaceae) have promising antimycobacterial and intracellular activity

Aro, Abimbola Obemisola; Dzoyem, Jean Paul; Awouafack, Maurice D.; Selepe, Mamoalosi A.; Eloff, Jacobus Nicolaas; McGaw, Lyndy Joy (BioMed Central, 2019-05-22)

BACKGROUND : Tuberculosis is a deadly disease caused by Mycobacterium species. The use of medicinal plants is an ancient global practice for the treatment and prevention of diverse ailments including tuberculosis. The aim ...
In vitro antimycobacterial, apoptosis-inducing potential, and immunomodulatory activity of some Rubiaceae species

Aro, Abimbola Obemisola; Dzoyem, Jean Paul; Goddard, Amelia; Fonteh, Pascaline; Kayoka-Kabongo, Prudence Ngalula; McGaw, Lyndy Joy (Frontiers Media, 2019-03-05)

Tuberculosis (TB), a disease caused by microorganisms of the Mycobacterium tuberculosis complex, infects almost one-third of the world’s population. The TB epidemic has been further exacerbated by the emergence of multi, ...
Isolation of endophytic fungi from South African plants, and screening for their antimicrobial and extracellular enzymatic activities and presence of type I polyketide synthases

Abdalla, Muna Ali; Aro, Abimbola Obemisola; Gado, Dorcas A.; Passari, Ajit Kumar; Mishra, Vineet Kumar; Singh, Bhim Pratap; McGaw, Lyndy Joy (Elsevier, 2020-11)

Endophytes are bacteria or fungi which live inside the host plant and participate in many biological processes without causing disease or other adverse effects. Endophytes are recognised as a rich source of secondary ...
Noxious to ecosystems, but relevant to pharmacology : four South African alien invasive plants with pharmacological potential

Omokhua-Uyi, Aitebiremen Gift; Madikizela, Balungile; Aro, Abimbola Obemisola; Uyi, O.O.; Van Staden, Johannes; McGaw, Lyndy Joy (Elsevier, 2018-07)

Alien invasive plants pose a huge threat to natural and semi-natural ecosystems in their introduced ranges thereby compromising ecosystem integrity. However, anecdotal and empirical evidence suggests that some invasive ...
Some South African Rubiaceae tree leaf extracts have antimycobacterial activity against pathogenic and non-pathogenic Mycobacterium species

Aro, Abimbola Obemisola; Dzoyem, Jean Paul; Hlokwe, Tiny Motlatso; Madoroba, Evelyn; Eloff, Jacobus Nicolaas; McGaw, Lyndy Joy (Wiley, 2015-07)

Tuberculosis (TB) caused by Mycobacterium tuberculosis remains an ongoing threat to human health. Many plant species contain antimycobacterial compounds which may serve as template molecules for new anti-TB drugs. The ...
Synthesis, biological evaluation and molecular docking of novel indole-aminoquinazoline hybrids for anticancer properties

Mphahlele, Malose J.; Mmonwa, Mmakwena M.; Aro, Abimbola Obemisola; McGaw, Lyndy Joy; Choong, Yee Siew (MDPI Publishing, 2018-07-31)

A series of indole-aminoquinazolines was prepared via amination of the 2-aryl-4-chloroquinazolines with the 7-amino-2-aryl-5-bromoindoles. It was then evaluated for cytotoxicity in vitro against human lung cancer (A549), ...

Now showing items 1-11 of 11

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Browsing Paraclinical Sciences by UP Author "Aro, Abimbola Obemisola"

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