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Browsing Research Articles (Genetics) by UP Author "Theron, Jacques"
Now showing items 1-8 of 8
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Guo, Yunze; Pretorius, Jakobus Maree; Xu, Qingyuan; Wu, Donglai; Bu, Zhigao; Theron, Jacques; Sun, Encheng (Springer, 2020-05)Epizootic hemorrhagic disease virus (EHDV) is a member of the genus Orbivirus, family Reoviridae, and has a genome consisting of 10 linear double-stranded (ds) RNA segments. The current reverse genetics system (RGS) for ...
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Pretorius, Jakobus Maree; Huismans, H. (Henk), 1942-; Theron, Jacques (Elsevier, 2015-12)Bluetongue virus (BTV), the type species of the genus Orbivirus within the family Reoviridae, has a genome consisting of 10 linear double-stranded RNA genome segments. Current reverse genetics approaches for engineering ...
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Maake, Lorens; Harvey, William T.; Rotherham, Lia; Opperman, Pamela Anne; Theron, Jacques; Reeve, Richard; Maree, Francois Frederick (Frontiers Media, 2020-09)Foot-and-mouth disease (FMD) continues to be a major burden for livestock owners in endemic countries and a continuous threat to FMD-free countries. The epidemiology and control of FMD in Africa is complicated by the ...
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Scott, Katherine Anne; Maake, Lorens; Botha, Elizabeth; Theron, Jacques; Maree, Francois Frederick (Elsevier, 2019-04)Foot-and-mouth disease (FMD) virus (FMDV) isolates show variation in their ability to withstand an increase in temperature. The FMDV is surprisingly thermolabile, even though this virus is probably subjected to a strong ...
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Ramulongo, Tovhowani Dapheny; Maree, Francois Frederick; Scott, Katherine; Opperman, Pamela Anne; Theron, Jacques (Elsevier, 2020-04)Foot-and-mouth disease (FMD) is a highly contagious vesicular disease of cloven-hoofed animals, which severely decreases livestock productivity. FMD virus (FMDV), the causative agent, initiates infection by interaction ...
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Mamabolo, Mpho Victoria; Theron, Jacques; Maree, Francois Frederick; Crampton, Michael (BioMed Central, 2020-01-07)The seven serotypes of foot-and-mouth disease virus (FMDV) differ on the surface exposed regions on the VP1, 2 and 3 proteins. Amongst the three, the VP1 protein has been produced the most for use in serotyping assays for ...
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Chitray, Melanie; Kotecha, Abhay; Nsamba, Peninah; Ren, Jingshan; Maree, Sonja; Ramulongo, Tovhowani; Paul, Guntram; Theron, Jacques; Fry, Elizabeth E.; Stuart, David I.; Maree, Francois Frederick (Public Library of Science, 2020-09-29)Field isolates of foot-and-mouth disease viruses (FMDVs) utilize integrin-mediated cell entry but many, including Southern African Territories (SAT) viruses, are difficult to adapt to BHK- 21 cells, thus hampering ...
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Ferreira-Venter, Linda; Venter, Eudri; Theron, Jacques; Van Staden, Vida (Elsevier, 2019-05)The African horse sickness virus non-structural protein 3 (NS3) is involved in the final stages of infection. To gain insight into the function of different NS3 domains, we generated reverse genetics-derived mutants, each ...
Now showing items 1-8 of 8