Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Bester, Megan Jean; Gaspar, Anabella Regina Marques(Elsevier, 2020-10)
Type 2 diabetes is a multifactorial disease and drugs with multifunctional properties are required. The peptide, SQSPA, was reported to be a potent and gastrointestinally stable α-glucosidase inhibitory peptide. In this ...
Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Bester, Megan Jean; Neitz, Albert Walter Herman; Gaspar, Anabella Regina Marques(Elsevier, 2019-02)
Antidiabetic agents with multiple targets have the greatest pharmaceutical potential. In this study, three α-glucosidase inhibitory peptides, PFP, YPL and YPG, were investigated for additional antidiabetic targets viz.; ...
Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Bester, Megan Jean; Neitz, Albert Walter Herman; Gaspar, Anabella Regina Marques(Springer, 2020-12)
Type 2 diabetes mellitus (T2DM) is a multifactorial disease that requires multiple therapeutic strategies for its management. Bioactive peptides with multiple anti-diabetic targets are attractive therapeutic molecules. The ...
Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Bester, Megan Jean; Neitz, Albert Walter Herman; Gaspar, Anabella Regina Marques(Bentham Science, 2019-07)
BACKGROUND : Peptide-based therapeutics offer a unique avenue for the development of novel agents for the treatment of diabetes mellitus including α-glucosidase inhibitors. The peptide, SQSPA, was reported to possess to α ...
