Browsing Research Articles (Genetics) by Author "Kappo, Abidemi P."

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An in vitro study on the combination effect of metformin and N-Acetyl cysteine against hyperglycaemia-induced cardiac damage

Johnson, Rabia; Sangweni, Nonhlakanipho F.; Mabhida, Sihle E.; Dludla, Phiwayinkosi V.; Mabasa, Lawrence; Riedel, Sylvia; Chapman, Charna; Mosa, Rebamang Anthony; Kappo, Abidemi P.; Louw, Johan; Muller, Christo J. F. (MDPI Publishing, 2019-11-21)

Chronic hyperglycaemia is a major risk factor for diabetes-induced cardiovascular dysfunction. In a hyperglycaemic state, excess production of reactive oxygen species (ROS), coupled with decreased levels of glutathione, ...
The triterpene, methyl-3β-hydroxylanosta-9,24-dien-21-oate (RA3), attenuates high glucose-induced oxidative damage and apoptosis by improving energy metabolism

Sangweni, Nonhlakanipho F.; Mosa, Rebamang Anthony; Dludla, Phiwayinkosi V.; Kappo, Abidemi P.; Opoku, Andy R.; Muller, Christo J. F.; Johnson, Rabia (Elsevier, 2021-05)

BACKGROUND: Hyperglycemia-induced cardiovascular dysfunction has been linked to oxidative stress and accelerated apoptosis in the diabetic myocardium. While there is currently no treatment for diabetic cardiomyopathy (DCM), ...

Now showing items 1-2 of 2

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