Browsing Genetics by Title

Browsing Genetics by Title

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  • A roadmap for Antarctic and Southern Ocean science for the next two decades and beyond 
    Kennicutt II, M.C.; Chown, Steven Loudon; Cassano, J.J.; Liggett, D.; Peck, L.S.; Massom, R.; Rintoul, S.R.; Storey, J.; Vaughan, D.G.; Wilson, T.J.; Allison, I.; Ayton, J.; Badhe, R.; Baeseman, J.; Barrett, P.J.; Bell, R.E.; Bertler, N.; Bo, S.; Brandt, A.; Bromwich, D.; Cary, S.C.; Clark, M.S.; Convey, P.; Costa, E.S.; Cowan, Don A.; Deconto, R.; Dunbar, R.; Elfring, C.; Escutia, C.; Francis, J.; Fricker, H.A.; Fukuchi, M.; Gilbert, N.; Gutt, J.; Havermans, C.; Hik, D.; Hosie, G.; Jones, G.; Kim, Y. D.; Le Maho, Y.; Lee, S.H.; Leppe, M.; Leitchenkov, G.; Li, X.; Lipenkov, V.; Lochte, K.; López-Martínez, J.; Lüdecke, C.; Lyons, W.; Marenssi, S.; Miller, H.; Morozova, P.; Naish, T.; Nayak, S.; Ravindra, R.; Retamales, J.; Ricci, C.A.; Rogan-Finnemore, M.; Ropert-Coudert, Y.; Samah, A.A.; Sanson, L.; Scambos, T.; Schloss, I.R.; Shiraishi, K.; Siegert, M.J.; Simões, J.C.; Storey, B.; Sparrow, M.D.; Wall, D.H.; Walsh, J.C.; Wilson, G.; Winther, J.G.; Xavier, J.C.; Yang, H.; Sutherland, W.J. (Cambridge University Press, 2015-02)
    Antarctic and Southern Ocean science is vital to understanding natural variability, the processes that govern global change and the role of humans in the Earth and climate system. The potential for new knowledge to be ...
  • Roadmap for naming uncultivated Archaea and Bacteria 
    Murray, Alison E.; Freudenstein, John; Gribaldo, Simonetta; Hatzenpichler, Roland; Hugenholtz, Philip; Kampfer, Peter; Konstantinidis, Konstantinos T.; Lane, Christopher E.; Papke, R. Thane; Parks, Donovan H.; Rossello-Mora, Ramon; Stott, Matthew B.; Sutcliffe, Iain C.; Thrash, J. Cameron; Venter, S.N. (Stephanus Nicolaas); Whitman, William B.; Acinas, Silvia G.; Amann, Rudolf I.; Anantharaman, Karthik; Armengaud, Jean; Baker, Brett J.; Barco, Roman A.; Bode, Helge B.; Boyd, Eric S.; Brady, Carrie Louise; Carini, Paul; Chain, Patrick S.G.; Colman, Daniel R.; DeAngelis, Kristen M.; De los Rios, Maria Asuncion; Estrada-de los Santos, Paulina; Dunlap, Christopher A.; Eisen, Jonathan A.; Emerson, David; Ettema, Thijs J.G.; Eveillard, Damien; Girguis, Peter R.; Hentschel, Ute; Hollibaugh, James T.; Hug, Laura A.; Inskeep, William P.; Ivanova, Elena P.; Klenk, Hans-Peter; Li, Wen-Jun; Lloyd, Karen G.; Loffler, Frank E.; Makhalanyane, Thulani Peter; Moser, Duane P.; Nunoura, Takuro; Palmer, Marike; Parro, Victor; Pedrós-Alio, Carlos; Probst, Alexander J.; Smits, Theo H.M.; Steen, Andrew D.; Steenkamp, Emma Theodora; Spang, Anja; Stewart, Frank J.; Tiedje, James M.; Vandamme, Peter; Wagner, Michael; Wang, Feng-Ping; Yarza, Pablo; Hedlund, Brian P.; Reysenbach, Anna-Louise (Nature Research, 2020-06-08)
    The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) has led to a surge in genome-based discoveries of members affiliated with Archaea and Bacteria, bringing with it a need to develop ...
  • The role of aDNA in understanding the coevolutionary patterns of human sexually transmitted infections 
    Pimenoff, Ville N.; Houldcroft, Charlotte J.; Rifkin, Riaan F.; Underdown, Simon (MDPI, 2018-07)
    Analysis of pathogen genome data sequenced from clinical and historical samples has made it possible to perform phylogenetic analyses of sexually transmitted infections on a global scale, and to estimate the diversity, ...
  • Role of African horsesickness virus protein NS3 in cytotoxicity and virus induced cytopathology 
    Meiring, Tracy Leonora (University of Pretoria, 2011-09-23)
    The viral determinants of African horsesickness virus (AHSV) cytopathology are not well understood. Several AHSV proteins may play a role, including non-structural protein NS3, a cytotoxic membrane protein that localises ...
  • The role of conserved residues in African horsesickness virus protein NS3 in intracellular localisation and cytotoxicity 
    Van de Merwe, Etienne (University of Pretoria, 2011-09-08)
    The role of the non-structural protein NS3 in the viral life cycle of African horsesickness virus (AHSV) is an active area of research. It has been shown to be involved in the lytic and nonlytic mechanisms of viral release. ...
  • The role of non-structural protein NS3 in the African horse sickness virus infection cycle in mammalian and insect cells 
    Ferreira-Venter, Linda (University of Pretoria, 2020-04-02)
    African horse sickness is an economically important equid disease caused by African horse sickness virus (AHSV). Upon infection, the virus produces seven structural proteins that constitute the virus particle, and four ...
  • Role of plants in anticancer drug discovery 
    Khazir, Jabeena; Mir, Bilal Ahmad; Pilcher, Lynne A.; Riley, Darren L. (Elsevier, 2014-02)
    Cancer is one of the major causes of death and the number of new cases, as well as the number of individuals living with cancer, is expanding continuously. Worldwide the alarming rise in mortality rate due to cancer has ...
  • The role of reactive oxygen species in adipogenic differentiation 
    De Villiers, Danielle; Potgieter, Marnie; Ambele, Melvin Anyasi; Adam, Ladislaus; Durandt, Chrisna; Pepper, Michael Sean (Springer, 2017-11)
    Interest in reactive oxygen species and adipocyte differentiation/adipose tissue function is steadily increasing. This is due in part to a search for alternative avenues for combating obesity, which results from the excess ...
  • The role PTEN mutations in hyperplasia and carcinoma of the endometrium 
    Jamison, Johanna Catharina Aletta (University of Pretoria, 2006-06-02)
    Endometrial carcinoma, which is preceded by non-malignant hyperplasia, is the fifth most common cancer in women worldwide. Various genetic alterations appear to be early events in the pathogenesis of endometrial cancer. ...
  • Roles of plant volatiles in defence against microbial pathogens and microbial exploitation of volatiles 
    Hammerbacher, Almuth; Coutinho, Teresa A.; Gershenzon, Jonathan (Wiley, 2019-10)
    Plants emit a large variety of volatile organic compounds during infection by pathogenic microbes, including terpenes, aromatics, nitrogen‐containing compounds, and fatty acid derivatives, as well as the volatile plant ...
  • Rosellinia necatrix infection induces differential gene expression between tolerant and susceptible avocado rootstocks 
    Zumaquero, Adela; Martınez-Ferri, Elsa; Matas, Antonio J.; Reeksting, Bianca J.; Olivier, Nicholas Abraham; Pliego-Alfaro, Fernando; Barcelo, Araceli; Van den Berg, Noelani (Public Library of Science, 2019-02)
    Rosellinia necatrix is the causal agent of avocado white root rot (WRR). Control of this soilborne disease is difficult, and the use of tolerant rootstocks may present an effective method to lessen its impact. To date, ...
  • Saprophytic and pathogenic fungi in the Ceratocystidaceae differ in their ability to metabolize plant-derived sucrose 
    Van der Nest, Magrieta Aletta; Steenkamp, Emma Theodora; McTaggart, Alistair R.; Trollip, Conrad; Godlonton, T.; Sauerman, E.; Roodt, Danielle; Naidoo, Kershney; Coetzee, Martin Petrus Albertus; Wilken, Pieter Markus; Wingfield, Michael J.; Wingfield, Brenda D. (BioMed Central, 2015-12-07)
    BACKGROUND : Proteins in the Glycoside Hydrolase family 32 (GH32) are carbohydrate-active enzymes known as invertases that hydrolyse the glycosidic bonds of complex saccharides. Fungi rely on these enzymes to gain access ...
  • Sciarid pests (Diptera: Sciaridae) from undercover crop production in South Africa 
    Katumanyane, Agil; Kanzi, Aquillah M.; Malan, Antoinette P. (Academy of Science of South Africa, 2020-03)
    Fungus gnats (sciarids) are among the most important pests in undercover crop production. They cause direct physical damage to plant roots, transfer fungal pathogens and create entry points for soil-borne plant pathogens. ...
  • Screening for specific mutations in malignant hyperthermia susceptible families 
    Havenga, Yolande (University of Pretoria, 2010-09-13)
    Malignant hyperthermia (MH) is an autosomal dominant pharmacogenetic disorder (Deufel et aI., 1992). It is potentially fatal and one of the leading causes of death due to anaesthesia. An MH episode is triggered when MH ...
  • Sea-level changes, river capture and the evolution of populations of the Eastern Cape and fiery redfins (Pseudobarbus afer and Pseudobarbus phlegethon, Cyprinidae) across multiple river systems in South Africa 
    Swartz, E.R. (Ernst Roelof); Skelton, Paul H. (Paul Harvey); Bloomer, Paulette (Blackwell, 2007-12)
    AIM: The phylogeography of the two closely related species Pseudobarbus afer and Pseudobarbus phlegethon was investigated to assess the association of evolutionary processes, inferred from mitochondrial DNA (mtDNA) sequence ...
  • The seagrass methylome is associated with variation in photosynthetic performance among clonal shoots 
    Jueterbock, Alexander; Boström, Christoffe; Coyer, James A.; Olsen, Jeanine L.; Kopp, Martina; Dhanasiri, Anusha K.S.; Smolina, Irina; Arnaud-Haond, Sophie; Van de Peer, Yves; Hoarau, Galice (Frontiers Media, 2020-09)
    Evolutionary theory predicts that clonal organisms are more susceptible to extinction than sexually reproducing organisms, due to low genetic variation and slow rates of evolution. In agreement, conservation management ...
  • Selection of Clostridium spp. in biological sand filters neutralizing synthetic acid mine drainage 
    Ramond, Jean-Baptiste; Welz, Pamela J.; Le Roes-Hill, Marilize; Tuffin, Marla I.; Burton, Stephanie G.; Cowan, Don A. (Wiley-Blackwell, 2014-03)
    In this study, three biological sand filter (BSF) were contaminated with a synthetic iron- [1500 mg L⁻¹ Fe(II), 500 mg L⁻¹ Fe(III)] and sulphate-rich (6000 mg L⁻¹ SO₄²⁻) acid mine drainage (AMD) (pH = 2), for 24 days, to ...
  • Selection of diazotrophic bacterial communities in biological sand filter mesocosms used for the treatment of phenolic-laden wastewater 
    Ramond, Jean-Baptiste; Tuffin, Marla I.; Welz, Pamela J.; Burton, Stephanie G.; Cowan, Don A. (Springer, 2013-10)
    Agri effluents such as winery or olive mill wastewaters are characterized by high phenolic concentrations. These compounds are highly toxic and generally refractory to biodegradation. Biological sand filters (BSFs) ...
  • Semi-synthetic analogues of cryptolepine as a potential source of sustainable drugs for the treatment of malaria, human African trypanosomiasis, and cancer 
    Abacha, Yabalu Z.; Forkuo, Arnold Donkor; Gbedema, Stephen Y.; Mittal, Nimisha; Ottilie, Sabine; Rocamora, Frances; Winzeler, Elizabeth A.; Van Schalkwyk, Donelly A.; Kelly, John M.; Taylor, Martin C.; Reader, Janette; Birkholtz, Lyn-Marie; Lisgarten, David R.; Cockcroft, Jeremy K.; Lisgarten, John N.; Palmer, Rex A.; Talbert, Rosemary C.; Shnyder, Steven D.; Wright, Colin W. (Frontiers Media, 2022-04)
    The prospect of eradicating malaria continues to be challenging in the face of increasing parasite resistance to antimalarial drugs so that novel antimalarials active against asexual, sexual, and liver-stage malaria parasites ...
  • Sequence data reflect the introduction pathways of the Sirex woodwasp parasitoid, Ibalia leucospoides (Ibaliidae, Hymenoptera) 
    Hurley, Brett Phillip; Fitza, Katrin N.E.; Wingfield, Michael J.; Slippers, Bernard (Wiley, 2020-05)
    The parasitoid wasp Ibalia leucospoides is native to the northern hemisphere and has been introduced to the southern hemisphere as a biological control agent for the invasive woodwasp Sirex noctilio. Two subspecies of the ...