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Browsing Research Articles (Companion Animal Clinical Studies) by Author "Dahan, Arik"

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DP-155, a lecithin derivative of indomethacin, is a novel nonsteroidal antiinflammatory drug for analgesia and Alzheimer's disease therapy

Dvir, Eran; Elman, Anat; Simmons, Danielle; Shapiro, Israel; Duvdevani, Revital; Dahan, Arik; Hoffman, Amnon; Friedman, Jonathan E. (Blackwell, 2007-06)

DP-155 is a lipid prodrug of indomethacin that comprises the latter conjugated to lecithin at position sn-2 via a 5-carbon length linker. It is cleaved by phospholipase A2 (PLA)2 to a greater extent than similar compounds ...

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