Browsing Research Articles (Microbiology and Plant Pathology) by Author "Kotecha, Abhay"

Browsing Research Articles (Microbiology and Plant Pathology) by Author "Kotecha, Abhay"

Sort by: Order: Results:

  • Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design 
    Kotecha, Abhay; Seago, Julian; Scott, Katherine Anne; Burman, Alison; Loureiro, Silvia; Ren, Jingshan; Porta, Claudine; Ginn, Helen M.; Jackson, Terry; Perez-Martin, Eva; Siebert, C. Alistair; Paul, Guntram; Huiskonen, Juha T.; Jones, Ian M.; Esnouf, Robert M.; Fry, Elizabeth E.; Maree, Francois Frederick; Charleston, Bryan; Stuart, David I. (Nature Publishing Group, 2015-10)
    Virus capsids are primed for disassembly, yet capsid integrity is key to generating a protective immune response. Foot-and-mouth disease virus (FMDV) capsids comprise identical pentameric protein subunits held together ...
  • Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses 
    Chitray, Melanie; Kotecha, Abhay; Nsamba, Peninah; Ren, Jingshan; Maree, Sonja; Ramulongo, Tovhowani; Paul, Guntram; Theron, Jacques; Fry, Elizabeth E.; Stuart, David I.; Maree, Francois Frederick (Public Library of Science, 2020-09-29)
    Field isolates of foot-and-mouth disease viruses (FMDVs) utilize integrin-mediated cell entry but many, including Southern African Territories (SAT) viruses, are difficult to adapt to BHK- 21 cells, thus hampering ...