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Browsing Research Articles (Biochemistry) by Subject "Vitamin B6"

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Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum

Reeksting, S.B. (Shaun Bernard); Muller, Ingrid B.; Burger, Pieter Buys; Burgos, Emmanuel S.; Salmon, Laurent; Louw, Abraham Izak; Birkholtz, Lyn-Marie; Wrenger, Carsten (Portland Press on behalf of the Biochemical Society, 2013)

Malaria tropica is a devastating infectious disease caused by Plasmodium falciparum. This parasite synthesizes vitamin B6 de novo via the pyridoxal 5-phosphate (PLP) synthase enzymatic complex consisting of PfPdx1 and ...

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