Browsing Research Articles (Biochemistry) by Subject "N-terminal loop"

Browsing Research Articles (Biochemistry) by Subject "N-terminal loop"

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  • The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold 
    Dossang, Anthony C.G.; Motshwene, Precious G.; Yang, Yang; Symmons, Martyn F.; Bryant, Clare E.; Borman, Satty; George, Julie; Weber, Alexander N.R.; Gay, Nicholas J. (Nature Publishing Group, 2016-11-23)
    Activation of Toll-like receptors induces dimerization and the recruitment of the death domain (DD) adaptor protein MyD88 into an oligomeric post receptor complex termed the Myddosome. The Myddosome is a hub for inflammatory ...