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Browsing Research Articles (Biochemistry) by Subject "High-throughput assay"

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Artemisone and artemiside - potent pan-reactive antimalarial agents that also synergize redox imbalance in P. falciparum transmissible gametocyte stages

Coertzen, Dina; Reader, Janette; Van der Watt, Mariette Elizabeth; Nondaba, Sindisiwe; Gibhard, Liezl; Wiesner, Lubbe; Smith, Peter; D'Alessandro, Sarah; Taramelli, Donatella; Wong, Ho Ning; Du Preez, Jan L.; Wu, Ronald Wai Keung; Birkholtz, Lyn-Marie; Haynes, Richard K. (American Society for Microbiology, 2018-08)

The emergence of resistance towards artemisinin combination therapies (ACTs) by the malaria parasite Plasmodium falciparum has the potential to severely compromise malaria control. Therefore, development of new artemisinins ...

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