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Browsing Research Articles (Biochemistry) by UP Author "Theron, Jacques"
Now showing items 1-8 of 8
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Guo, Yunze; Pretorius, Jakobus Maree; Xu, Qingyuan; Wu, Donglai; Bu, Zhigao; Theron, Jacques; Sun, Encheng (Springer, 2020-05)Epizootic hemorrhagic disease virus (EHDV) is a member of the genus Orbivirus, family Reoviridae, and has a genome consisting of 10 linear double-stranded (ds) RNA segments. The current reverse genetics system (RGS) for ...
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Maake, Lorens; Harvey, William T.; Rotherham, Lia; Opperman, Pamela Anne; Theron, Jacques; Reeve, Richard; Maree, Francois Frederick (Frontiers Media, 2020-09)Foot-and-mouth disease (FMD) continues to be a major burden for livestock owners in endemic countries and a continuous threat to FMD-free countries. The epidemiology and control of FMD in Africa is complicated by the ...
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Scott, Katherine Anne; Maake, Lorens; Botha, Elizabeth; Theron, Jacques; Maree, Francois Frederick (Elsevier, 2019-04)Foot-and-mouth disease (FMD) virus (FMDV) isolates show variation in their ability to withstand an increase in temperature. The FMDV is surprisingly thermolabile, even though this virus is probably subjected to a strong ...
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Bekker, Shani; Potgieter, Christiaan A.; Van Staden, Vida; Theron, Jacques (MDPI, 2022-10-04)African horse sickness is a deadly and highly infectious disease of equids, caused by African horse sickness virus (AHSV). AHSV is one of the most economically important members of the Orbivirus genus. AHSV is transmitted ...
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Ramulongo, Tovhowani Dapheny; Maree, Francois Frederick; Scott, Katherine; Opperman, Pamela Anne; Theron, Jacques (Elsevier, 2020-04)Foot-and-mouth disease (FMD) is a highly contagious vesicular disease of cloven-hoofed animals, which severely decreases livestock productivity. FMD virus (FMDV), the causative agent, initiates infection by interaction ...
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Mamabolo, Mpho Victoria; Theron, Jacques; Maree, Francois Frederick; Crampton, Michael (BioMed Central, 2020-01-07)The seven serotypes of foot-and-mouth disease virus (FMDV) differ on the surface exposed regions on the VP1, 2 and 3 proteins. Amongst the three, the VP1 protein has been produced the most for use in serotyping assays for ...
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Chitray, Melanie; Kotecha, Abhay; Nsamba, Peninah; Ren, Jingshan; Maree, Sonja; Ramulongo, Tovhowani; Paul, Guntram; Theron, Jacques; Fry, Elizabeth E.; Stuart, David I.; Maree, Francois Frederick (Public Library of Science, 2020-09-29)Field isolates of foot-and-mouth disease viruses (FMDVs) utilize integrin-mediated cell entry but many, including Southern African Territories (SAT) viruses, are difficult to adapt to BHK- 21 cells, thus hampering ...
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Ferreira-Venter, Linda; Venter, Eudri; Theron, Jacques; Van Staden, Vida (Elsevier, 2019-05)The African horse sickness virus non-structural protein 3 (NS3) is involved in the final stages of infection. To gain insight into the function of different NS3 domains, we generated reverse genetics-derived mutants, each ...
Now showing items 1-8 of 8