The ability to target human-mosquito parasite transmission challenges global
malaria elimination. However, it is not obvious what a transmission-blocking
drug will look like; should it 1) target only parasite transmission ...
BACKGROUND : The discovery of malaria transmission-blocking compounds is seen as key to malaria elimination strategies and gametocyte-screening platforms are critical filters to identify active molecules. However, unlike ...
Becker, John V.W.; Mtwisha, Linda; Crampton, Bridget Genevieve; Stoychev, Stoyan H.; Van Brummelen, Anna Catharina; Reeksting, Shaun Bernard; Louw, Abraham Izak; Birkholtz, Lyn-Marie; Mancama, Dalu(BioMed Central, 2010-04)
BACKGROUND: Plasmodium falciparum, the causative agent of severe human malaria, has evolved to become resistant to previously successful antimalarial chemotherapies, most notably chloroquine and the antifolates. The ...
