Browsing Research Articles (Biochemistry) by Title

Browsing Research Articles (Biochemistry) by Title

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  • Lactobacillus casei expressing Internalins A and B reduces Listeria monocytogenes interaction with Caco-2 cells in vitro 
    Mathipa, Moloko Gloria; Thantsha, Mapitsi Silvester; Bhunia, Arun K. (Wiley Open Access, 2019-07)
    Listeria monocytogenes has been implicated in a number of outbreaks including the recent largest outbreak in South Africa. Current methods for prevention of foodborne L. monocytogenes infection are inadequate, thus raising ...
  • A Lanosteryl triterpene (RA-3) exhibits antihyperuricemic and nephroprotective effects in rats 
    Hlophe, Nomadlozi Blessings; Opoku, Andrew Rowland; Osunsanmi, Foluso Oluwagbemiga; Djarova-Daniels, Trayana Georgieva; Lawal, Oladipupo Adejumobi; Mosa, Rebamang Anthony (MDPI, 2020-09)
    Considering the global health threat posed by kidney disease burden, a search for new nephroprotective drugs from our local flora could prove a powerful strategy to respond to this health threat. In this study we ...
  • Large-scale generation and analysis of filamentous fungal DNA barcodes boosts coverage for kingdom fungi and reveals thresholds for fungal species and higher taxon delimitation 
    Vu, D.; Groenewald, M.; De Vries, M.; Gehrmann, T.; Stielow, B.; Eberhardt, U.; Al-Hatmi, A.; Groenewald, Johannes Zacharias; Cardinali, G.; Houbraken, J.; Boekhout, T.; Crous, Pedro W.; Robert, V.; Verkley, G.J.M. (Elsevier, 2019-03)
    Species identification lies at the heart of biodiversity studies that has in recent years favoured DNA-based approaches. Microbial Biological Resource Centres are a rich source for diverse and high-quality reference materials ...
  • LEA proteins and the evolution of the WHy domain 
    Mertens, Jasmin; Aliyu, Habibu; Cowan, Don A. (American Society for Microbiology, 2018-05)
    The LEA family is composed of a diverse collection of multi-domain and multi-functional proteins, found in all three Domains of the Tree of Life, but particularly common in plants. Most members of the family are known to ...
  • Lecanosticta acicola : a growing threat to expanding global pine forests and plantations 
    Van der Nest, Ariska; Wingfield, Michael J.; Janoušek, Josef; Barnes, Irene (British Society for Plant Pathology and John Wiley & Sons Ltd, 2019-10)
    Lecanosticta acicola causes brown spot needle blight (BSNB) of Pinus species. The pathogen occurs mostly in the Northern Hemisphere but has also been reported in Central America and Colombia. BSNB can lead to stunted growth ...
  • Lessons from a major pest invasion : the polyphagous shot hole borer in South Africa 
    Paap, Trudy; Wingfield, Michael J.; De Beer, Z. Wilhelm; Roets, Francois (AOSIS Open Journals, 2020-11-26)
    The arrival and establishment of invasive forest pests can cause devastating environmental damage and great economic impact. For example, the cost over the past decade of dealing with the arrival of a single invasive beetle ...
  • Lifespan prolonging mechanisms and insulin upregulation without fat accumulation in long-lived reproductives of a higher termite 
    Seite, Sarah; Harrison, Mark C.; Sillam-Dusses, David; Lupoli, Roland; Van Dooren, Tom J.M.; Robert, Alain; Poissonnier, Laure-Anne; Lemainque, Arnaud; Renault, David; Acket, Sebastien; Andrieu, Muriel; Viscarra, Jose; Sul, Hei Sook; De Beer, Z. Wilhelm; Bornberg-Bauer, Erich; Vasseur-Cognet, Mireille (Nature Publishing, 2022-01)
    Kings and queens of eusocial termites can live for decades, while queens sustain a nearly maximal fertility. To investigate the molecular mechanisms underlying their long lifespan, we carried out transcriptomics, lipidomics ...
  • Limits of life and the habitability of Mars : the ESA space experiment BIOMEX on the ISS 
    De Vera, Jean-Pierre; Alawi, Mashal; Backhaus, Theresa; Baque, Mickael; Billi, Daniela; Bottger, Ute; Berger, Thomas; Bohmeier, Maria; Cockell, Charles; Demets, Rene; De la Torre Noetzel, Rosa; Edwards, Howell; Elsaesser, Andreas; Fagliarone, Claudia; Fiedler, Annelie; Foing, Bernard; Foucher, Frederic; Fritz, Jorg; Hanke, Franziska; Herzog, Thomas; Horneck, Gerda; Hubers, Heinz-Wilhelm; Huwe, Bjorn; Joshi, Jasmin; Kozyrovska, Natalia; Kruchten, Martha; Lasch, Peter; Lee, Natuschka; Leuko, Stefan; Leya, Thomas; Lorek, Andreas; Martınez-Frıas, Jesus; Meessen, Joachim; Moritz, Sophie; Moeller, Ralf; Olsson-Francis, Karen; Onofri, Silvano; Ott, Sieglinde; Pacelli, Claudia; Podolich, Olga; Rabbow, Elke; Reitz, Gunther; Rettberg, Petra; Reva, Oleg N.; Rothschild, Lynn; Sancho, Leo Garcia; Schulze-Makuch, Dirk; Selbmann, Laura; Serrano, Paloma; Szewzyk, Ulrich; Verseux, Cyprien; Wadsworth, Jennifer; Wagner, Dirk; Westall, Frances; Wolter, David; Zucconi, Laura (Mary Ann Liebert, 2019-02)
    BIOMEX (BIOlogy and Mars EXperiment) is an ESA/Roscosmos space exposure experiment housed within the exposure facility EXPOSE-R2 outside the Zvezda module on the International Space Station (ISS). The design of the ...
  • The Litsea genome and the evolution of the laurel family 
    Chen, Yi-Cun; Li, Zhen; Zhao, Yun-Xiao; Gao, Ming; Wang, Jie-Yu; Liu, Ke-Wei; Wang, Xue; Wu, Li-Wen; Jiao, Yu-Lian; Xu, Zi-Long; He, Wen-Guang; Zhang, Qi-Yan; Liang, Chieh-Kai; Hsiao, Yu-Yun; Zhang, Di-Yang; Lan, Si-Ren; Huang, Laiqiang; Xu, Wei; Tsai, Wen-Chieh; Liu, Zhong-Jian; Van de Peer, Yves; Wang, Yang-Dong (Nature Publishing Group, 2020-04-03)
    The laurel family within the Magnoliids has attracted attentions owing to its scents, variable inflorescences, and controversial phylogenetic position. Here, we present a chromosomelevel assembly of the Litsea cubeba ...
  • Local antagonism and resource partitioning between two invasive pine plantation pests 
    Wondafrash, Mesfin; Slippers, Bernard; Hurley, Brett Phillip; Garnas, Jeffrey R. (Wiley, 2019-08)
    The woodwasp Sirex noctilio Fabricius, native to Eurasia and North Africa, regularly co‐occurs with a North American origin Pissodes sp. on Pinus trees in South Africa. The nature of this co‐occurrence and potential impacts ...
  • Long non-coding RNAs in the human genome acquired by horizontal gene transfer 
    Pierneef, Rian Ewald; Clasen, Frederick Johannes; Bezuidt, Keoagile Ignatius Oliver; Reva, Oleg N. (Bentham Open, 2018)
    BACKGROUND : Horizontal gene transfer of mobile genetic elements is an essential component of prokaryotic evolution. These insertion events in eukaryotes and particularly in the human genome have been investigated by ...
  • Loss of wood formation genes in monocot genomes 
    Roodt, Danielle; Li, Zhen; Van de Peer, Yves; Mizrachi, Eshchar (Oxford University Press, 2019-07)
    Woodiness (secondary xylemderived from vascular cambium) has been gained and lostmultiple times in the angiosperms, but has been lost ancestrally in all monocots. Here, we investigate the conservation of genes involved ...
  • Low genetic diversity and strong geographic structure in introduced populations of the Eucalyptus foliar pathogen Teratosphaeria destructans 
    Havenga, Minette; Wingfield, Brenda D.; Wingfield, Michael J.; Dreyer, Leanne Laurette; Roets, Francois; Chen, ShuaiFei; Aylward, Janneke (Wiley, 2020-10)
    The aggressive Eucalyptus leaf pathogen, Teratosphaeria destructans, causes widespread damage in tropical and subtropical Eucalyptus‐growing regions of Indonesia, China, Thailand, East Timor, Vietnam, Lao, and South Africa. ...
  • Machine learning uses chemo-transcriptomic profiles to stratify antimalarial compounds with similar mode of action 
    Van Heerden, Ashleigh; Van Wyk, Roelof Daniel Jacobus; Birkholtz, Lyn-Marie (Frontiers Media, 2021-06)
    The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different to current antimalarials. Phenotypic screening has delivered thousands of promising ...
  • MADIBA : A web server toolkit for biological interpretation of Plasmodium and plant gene clusters 
    Law, Philip J.; Claudel-Renard, Clotilde; Joubert, Fourie; Louw, Abraham Izak; Berger, David Kenneth (BioMed Central, 2008)
    BACKGROUND: Microarray technology makes it possible to identify changes in gene expression of an organism, under various conditions. Data mining is thus essential for deducing significant biological information such as the ...
  • Mainstreams of horizontal gene exchange in enterobacteria : consideration of the outbreak of enterohemorrhagic E. coli O104:H4 in Germany in 2011 
    Bezuidt, Keoagile Ignatius Oliver; Pierneef, Rian Ewald; Mncube, Kingdom; Lima-Mendez, Gipsi; Reva, Oleg N. (Public Library of Science, 2011-10-14)
    BACKGROUND: Escherichia coli O104:H4 caused a severe outbreak in Europe in 2011. The strain TY-2482 sequenced from this outbreak allowed the discovery of its closest relatives but failed to resolve ways in which it originated ...
  • Maternal effects should be considered in the establishment of forestry plantations 
    Vivas, Maria; Wingfield, Michael J.; Slippers, Bernard (Elsevier, 2020-03)
    Breeding strategies for plants focus on the genetic influence on their phenotypes. However, the phenotype is not only the outcome of the genotype or the environmental conditions under which plants grow. It is important to ...
  • Maternal environment regulates morphological and physiological traits in Eucalyptus grandis 
    Vivas, Maria; Rolo, Victor; Wingfield, Michael J.; Slippers, Bernard (Elsevier, 2019-01)
    The phenotype of a plant can be shaped by the biotic and abiotic conditions to which their parents are subjected. This phenotypic plasticity known as maternal environmental effect occurs regardless of the changes in the ...
  • Mating genes in Calonectria and evidence for a heterothallic ancestral state 
    Li, JieQiong; Wingfield, Brenda D.; Wingfield, Michael J.; Barnes, Irene; Fourie, Arista; Crous, Pedro W.; Chen, S.F. (Naturalis Biodiversity Center and Centraalbureau voor Schimmelcultures, 2020-03-17)
    The genus Calonectria includes many important plant pathogens with a wide global distribution. In order to better understand the reproductive biology of these fungi, we characterised the structure of the mating type ...
  • Mating strategy and mating type distribution in six global populations of the Eucalyptus foliar pathogen Teratosphaeria destructans 
    Havenga, Minette; Wingfield, Brenda D.; Wingfield, Michael J.; Roets, Francois; Dreyer, Leanne Laurette; Tatham, Catherine; Duong, Tuan A.; Wilken, Pieter Markus; Chen, ShuaiFei; Aylward, Janneke (Elsevier, 2020-04)
    Teratosphaeria destructans is an aggressive fungal pathogen causing leaf and shoot blight on young Eucalyptus trees in plantations. The disease occurs across tropical and subtropical regions of South East Asia and has ...