Browsing Research Articles (School of Health Systems and Public Health (SHSPH)) by UP Author "Birkholtz, Lyn-Marie"

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Adapt or die : targeting unique transmission-stage biology for malaria elimination

Van der Watt, Mariette Elizabeth; Reader, Janette; Birkholtz, Lyn-Marie (Frontiers Media S.A., 2022-06-09)

Plasmodium parasites have a complex life cycle that includes development in the human host as well as the Anopheles vector. Successful transmission of the parasite between its host and vector therefore requires the ...
New transmission-selective antimalarial agents through hit-to-lead optimization of 2-([1,1 '-Biphenyl]-4-carboxamido)benzoic acid derivatives

Reader, Janette; Opperman, Daniel; Van der Watt, Mariette Elizabeth; Theron, Anjo; Leshabane, Meta Kgaogelo; Da Rocha, Michelle; Turner, Jonathan; Garrabrant, Kathleen; Pina, Ivett; Mills, Catherine; Woster, Patrick M.; Birkholtz, Lyn-Marie (Wiley, 2022-11)

Malaria elimination requires multipronged approaches, including the application of antimalarial drugs able to block humanto- mosquito transmission of malaria parasites. The transmissible gametocytes of Plasmodium ...
Sustainable malaria control : transdisciplinary approaches for translational applications

Birkholtz, Lyn-Marie; Bornman, Maria S. (Riana); Focke, Walter Wilhelm; Mutero, Clifford Maina; De Jager, Christiaan (BioMed Central, 2012-12-20)

With the adoption of the Global Malaria Action Plan, several countries are moving from malaria control towards elimination and eradication. However, the sustainability of some of the approaches taken may be questionable. Here, ...

Now showing items 1-3 of 3

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