Browsing Research Articles (Oral Pathology and Oral Biology) by Author "Radhakrishnan, Raghu"

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Rarβ expression in keratinocytes from potentially malignant oral lesions : the functional consequences of re-expression by de-methylating agents

Radhakrishnan, Raghu; Crane, Hannah L.; Daigneault, Marc; Ram Padam, Kanaka Sai; Hunter, K.D. (Keith) (MDPI, 2021-08-12)

Loss of RARβ2 expression by promoter methylation is an early event in oral carcinogenesis. Understanding the mechanisms and consequences of RARβ loss may aid in understanding the disappointing results of retinoid chemoprevention ...
Targeting HOX-PBX interactions causes death in oral potentially malignant and squamous carcinoma cells but not normal oral keratinocytes

Platais, Christopher; Radhakrishnan, Raghu; Ebensberger, Sven Niklander; Morgan, Richard; Lambert, Daniel W.; Hunter, K.D. (Keith) (BioMed Central, 2018-07-06)

BACKGROUND : High HOX gene expression has been described in many cancers, including oral squamous cell carcinoma and the functional roles of these genes are gradually being understood. The pattern of overexpression suggests ...

Now showing items 1-2 of 2

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