Browsing Research Articles (Oral Pathology and Oral Biology) by Author "Platais, Christopher"

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The role of HOX genes in head and neck squamous cell carcinoma

Platais, Christopher; Hakami, Fahad; Darda, Lav; Lambert, Daniel W.; Morgan, Richard; Hunter, K.D. (Keith) (Wiley, 2016-04)

Recent decades have witnessed the publication of numerous studies reporting alterations in the genome and transcriptome of head and neck squamous cell carcinoma (HNSCC). Currently, the utilisation of these alterations ...
Targeting HOX-PBX interactions causes death in oral potentially malignant and squamous carcinoma cells but not normal oral keratinocytes

Platais, Christopher; Radhakrishnan, Raghu; Ebensberger, Sven Niklander; Morgan, Richard; Lambert, Daniel W.; Hunter, K.D. (Keith) (BioMed Central, 2018-07-06)

BACKGROUND : High HOX gene expression has been described in many cancers, including oral squamous cell carcinoma and the functional roles of these genes are gradually being understood. The pattern of overexpression suggests ...

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