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Browsing Research Articles (Oral Pathology and Oral Biology) by Subject "De-methylating agent 5-Aza-2′ deoxycytidine (5-AZA-CdR)"

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Rarβ expression in keratinocytes from potentially malignant oral lesions : the functional consequences of re-expression by de-methylating agents

Radhakrishnan, Raghu; Crane, Hannah L.; Daigneault, Marc; Ram Padam, Kanaka Sai; Hunter, K.D. (Keith) (MDPI, 2021-08-12)

Loss of RARβ2 expression by promoter methylation is an early event in oral carcinogenesis. Understanding the mechanisms and consequences of RARβ loss may aid in understanding the disappointing results of retinoid chemoprevention ...

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