Browsing Research Articles (Anatomy and Physiology) by Subject "Endothelioma"

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Inhibition of phosphoinositide 3-kinase is associated with reduced angiogenesis and an altered expression of angiogenic markers in endothelioma cells

Mabeta, Peaceful Lucy (Elsevier, 2014-06)

The phosphoinositide 3-kinase (PI3k) signaling pathway is involved in the regulation of numerous cellular activities. The pathway has also been implicated in the development of various tumors. In the context of vascular ...
PF573,228 inhibits vascular tumor cell growth, migration as well as angiogenesis, induces apoptosis and abrogates PRAS40 and S6RP phosphorylation

Mabeta, Peaceful Lucy (De Gruyter Open, 2016-09)

PF573,228 is a compound that targets focal adhesion kinase (FAK), a non-receptor protein kinase, which is over-expressed in various tumors. The aim of this study was to evaluate the effects of PF573,228 on the cells ...

Now showing items 1-2 of 2

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