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Browsing Research Articles (Production Animal Studies) by UP Author "Smith, Tanja"

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Dose immunogenicity study of a plant-produced influenza virus-like particle vaccine in layer hens

Abolnik, Celia; Smith, Tanja; Wandrag, D.B.R. (Daniel); Murphy, Mark-Anthony; Rautenbach, Marizel; Olibile, Olebile; O'Kennedy, Martha Magaretha (Elsevier, 2022-06)

Avian influenza poses one of the largest known threats to global poultry production and human health, but effective poultry vaccines can reduce infections rates, production losses and prevent mortalities, and reduce viral ...
Efficacy of a plant-produced virus-like particle vaccine in chickens challenged with Influenza A H6N2 virus

Smith, Tanja; O’Kennedy, Martha M.; Wandrag, D.B.R. (Daniel); Adeyemi, Modupeore; Abolnik, Celia (Wiley Open Access, 2020-02)

The efficacy, safety, speed, scalability and cost-effectiveness of producing hemagglutinin-based virus-like particle (VLP) vaccines in plants are well-established for human influenza, but untested for the massive poultry ...
Immunogenicity of adjuvanted plant-produced SARS-CoV-2 Beta spike VLP vaccine in New Zealand white rabbits

O’Kennedy, Martha M.; Abolnik, Celia; Smith, Tanja; Motlou, Thopisang; Goosen, Kruger; Sepotokele, Kamogelo Mmapitso; Roth, Robyn; Du Preez, Ilse; Truyts, Alma; Stark, Hester C.; Magwaza, Martin; Mahanjana, Osborn; Verschoor, J.A. (Jan Adrianus), 1953-; Moore, Penny L.; Lemmer, Yolandy (Elsevier, 2023-03)

The outbreak of the SARS-CoV-2 global pandemic heightened the pace of vaccine development with various vaccines being approved for human use in a span of 24 months. The SARS-CoV-2 trimeric spike (S) surface glycoprotein, ...
The production of Newcastle disease virus-like particles in Nicotiana benthamiana as potential vaccines

Smith, Tanja; O'Kennedy, Martha; Ross, Craig S.; Lewis, Nicola S.; Abolnik, Celia (Frontiers Media, 2023-02)

Newcastle disease (ND) is a highly contagious viral respiratory and neurological disease that has a severe impact on poultry production worldwide. In the present study, an expression platform was established for the ...

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Browsing Research Articles (Production Animal Studies) by UP Author "Smith, Tanja"

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