The treatment of cholesterol : issues, effects and targets

Show simple item record Ker, James A. 2011-04-05T10:07:41Z 2011-04-05T10:07:41Z 2010-11
dc.description.abstract Statins are the most powerful cholesterol lowering drugs currently available. Statins inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG CoA) reductase, which leads to reduced cholesterol synthesis. In addition, low-density cholesterol receptors on the hepatocyte surface are upregulated, leading to increased clearance of cholesterol. The end result is a significant reduction in cholesterol levels, and a consequent significant reduction in mortality and cardiovascular events in the appropriate individual. en_US
dc.identifier.citation Ker, JA 2010, 'The treatment of cholesterol : issues, effects and targets', South African Family Practice, vol. 52, no. 6, pp. 523-524. [http;//] en_US
dc.identifier.issn 1726-426X (online)
dc.identifier.issn 1026-9177 (print)
dc.language.iso en en_US
dc.publisher South African Academy of Family Practice/Primary Care en_US
dc.rights © SAAFP en_US
dc.subject Cholesterol en_US
dc.subject Hypercholesterolemia en_US
dc.subject Treatment en_US
dc.subject Drug therapy en_US
dc.subject Statins en_US
dc.subject Effectivity en_US
dc.subject LDL cholesterol en_US
dc.subject Target en_US
dc.subject Risk en_US
dc.subject Prevention en_US
dc.subject Elderly en_US
dc.subject Time factors en_US
dc.subject Atherosclerosis en_US
dc.subject Safety en_US
dc.subject.lcsh Cholesterol -- Treatment
dc.title The treatment of cholesterol : issues, effects and targets en_US
dc.type Article en_US

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