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Browsing Research Articles (University of Pretoria) by UP Author "Zeevaart, Jan Rijn"
Now showing items 1-18 of 18
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Sathekge, Mike Machaba; Lengana, Thabo; Maes, Alex; Vorster, Mariza; Zeevaart, Jan Rijn; Lawal, Ismaheel Opeyemi; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2018-02)PURPOSE : The incidence of prostate cancer is 60% higher and the mortality rate is two- to three-times greater in black versus white men. We report on differences in 68Ga-PSMA-11 PET/CT imaging findings in 77 black ...
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Sathekge, Mike Machaba; Lengana, Thabo; Modiselle, Moshe; Vorster, Mariza; Zeevaart, Jan Rijn; Maes, Alex; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2017-04)BACKGROUND : To report on imaging findings using 68Ga-PSMAHBED- CC PET in a series of 19 breast carcinoma patients. METHODS : 68Ga-PSMA-HBED-CC PET imaging results obtained were compared to routinely performed staging ...
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Zeevaart, Jan Rijn; Wagener, Judith Marie; Neves, Maria; Costa, Maria Ceu; Rodrigues, Cristina; Dithebe, Midred K.; Kilian, Elmare; Cukrowski, Ignacy (Springer, 2010-01)99mTc-DMSA (dimercaptosuccinic acid) is known to be a safe and effective agent for static renal imaging. However, it has a long uptake time which is a limiting factor in diagnostic procedures and also leads to a relatively ...
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Nell, Margo Judith; Wagener, Judith Marie; Zeevaart, Jan Rijn; Kilian, Elmare; Mamo, Messai Adenew; Layh, Marcus; Coyanis, M.; Jansen van Rensburg, Connie E. (Elsevier, 2009-07)The anti-tumour activity of the Au (I) phosphine complex [Au(dppe2]Cl was first discovered in the mid 1980s although promising results were obtained it did not pass clinical studies because of its toxicity to organs such ...
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Ebenhan, Thomas; Gheysens, Olivier; Kruger, Hendrik G.; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (Hindawi Publishing, 2014-08)Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety of organisms including humans and, so far, hundreds of these structures have been isolated and characterised. They can be described ...
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Zeevaart, Jan Rijn; Szucs, Zoltan; Pulker, Tamsyn A.; Sello, Thato; Bracher, Jacqueline; Sathekge, Mike Machaba (Bentham Science, 2012-10-11)Phenylacetate has been reported to have a potent anti-proliferative and anti-differentiating effect in haematological malignancies and in solid tumours at non-toxic concentrations. This study is a preliminary investigation ...
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Ebenhan, Thomas; Vorster, Mariza; Marjanovic-Painter, Biljana; Wagener, Judith; Suthiram, J.; Modiselle, Moshe; Mokaleng, Botshelo B.; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI Publishing, 2015-08-14)Prostate-specific membrane antigen (PSMA), a type II glycoprotein, is highly expressed in almost all prostate cancers. By playing such a universal role in the disease, PSMA provides a target for diagnostic imaging of ...
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Vorster, Mariza; Modiselle, Moshe; Ebenhan, Thomas; Wagener, Carl; Sello, That; Zeevaart, Jan Rijn; Moshokwa, Evelyn; Sathekge, Mike Machaba (Hellenic Society of Nuclear Medicine, 2015-01)OBJECTIVE : Imaging with fluorine-18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) has, until recently provided disappointing results with low sensitivity ranging from 31%-64% ...
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Kweto, Bundjoko; Groot, D.R.; Stassen, E.; Suthiram, J.; Zeevaart, Jan Rijn (Springer, 2014-10)The purpose of this study was to determine the kinetics of the dissolution of a uranium residue in ammonium carbonate media. The residue is generated in the production of medical isotopes. The effects of parameters, such ...
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Szucs, Zoltan; Moolman, Danie (Daniel); Verryn, Sabine Marie Charlotte; Zeevaart, Jan Rijn (Springer, 2010-04)Research into a new method for separating palladium from rhodium, based on radiochemical principles, necessitated a re-investigation of the Gmelins Handbuch data indicating that Rh has allotropes. Two independent and ...
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Wagener, Judith Marie; Dithebe, Midred K.; Mogano, Daniel; Cukrowski, Ignacy; Zeevaart, Jan Rijn (South African Chemical Institute, 2008)99mTc-DMSA (DMSA=dimercaptosuccinic acid), the gold standard for static renal imaging, has a long uptake time, which is a limiting factor in diagnostic procedures and also leads to a relatively high radiation dose to ...
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Ebenhan, Thomas; Chadwick, Nicholas; Sathekge, Mike Machaba; Govender, Patrick; Govender, Thavendran; Kruger, Hendrik G.; Marjanovic-Painter, Biljana; Zeevaart, Jan Rijn (Elsevier, 2014-05)INTRODUCTION: Human antimicrobial peptides are of interest for the development of positron emission tomography (PET) tracers as they exhibit desirable characteristics that make them good candidates for targeting vectors. ...
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Ebenhan, Thomas; Zeevaart, Jan Rijn; Venter, Jacobus D.; Govender, Thavendran; Kruger, Gert H.; Jarvis, Neil V.; Sathekge, Mike Machaba (Society of Nuclear Medicine, 2014-02)Antimicrobial peptides such as ubiquicidin (UBI) are believed to differentiate between mammalian and bacterial or fungal cells. (99m)Tc-UBI29-41 was previously tested for detecting infection in humans using SPECT. For the ...
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Zeevaart, Jan Rijn; Wagener, Judith; Marjanovic-Painter, Biljana; Sathekge, Mike Machaba; Soni, Nischal; Zinn, Christa; Perkins, Gary; Smith, Suzanne (Wiley-Blackwell, 2013-07)Platinum agents continue to be the main chemotherapeutic agents used in the first-line and second-line treatments of cancer patients. It is important to fully understand the biological profile of these compounds in order ...
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Lawal, Ismaheel Opeyemi; Kleyhans, Janke; Mokoala, K.M.G. (Kgomotso); Vorster, Mariza; Ebenhan, Thomas; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (Bentham Science, 2021)Please read abstract in the article
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Kleynhans, Janke; Summers, Beverly; Sakr, Tamer; Zeevaart, Jan Rijn; Lundie, Maryke; Du Plessis, Samantha; Mosima, Lerato; Bentaleb, Naoual; Ekoume, Fany P.; Hlongwa, Khanyisile N.; Shambel, Seble; Mldophane, Amanda; Mangatha, Amreeta; More, Stuart (Springer, 2024-04)No abstract available.
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Mokaleng, Botshelo B.; Ebenhan, Thomas; Ramesh, Suhas; Govender, Thavendran; Kruger, Hendrik G.; Parboosing, Raveen; Hazari, Puja P.; Mishra, Anil K.; Marjanovic-Painter, Biljana; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (Hindawi Publishing, 2015)Noninvasive imaging is a powerful tool for early diagnosis and monitoring of various disease processes, such as infections. An alarming shortage of infection-selective radiopharmaceuticals exists for overcoming the diagnostic ...
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Dutta, Jyotibon; Baijnath, Sooraj; Somboro, Anou M.; Nagiah, Savania; Albericio, Fernando; De la Torre, Beatriz G.; Marjanovic-Painter, Biljana; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Kruger, Hendrik G.; Chuturgoon, Anil; Naicker, Tricia; Ebenhan, Thomas; Govender, Thavendran (Wiley, 2017-10)Bacterial infections are a major concern in the human health sector due to poor diagnosis and development of multidrug-resistant strains. PET/CT provides a means for the non-invasive detection and localization of the ...
Now showing items 1-18 of 18