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Browsing Research Articles (University of Pretoria) by Subject "G6PD defciency"

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Understanding human genetic factors influencing primaquine safety and efficacy to guide primaquine roll-out in a pre-elimination setting in southern Africa

Awandu, Shehu Shagari; Raman, Jaishree; Makhanthisa, Takalani Irene; Kruger, Philip; Frean, John; Bousema, Teun; Niemand, Jandeli; Birkholtz, Lyn-Marie (BioMed Central, 2018)

BACKGROUND: Primaquine (PQ) is recommended as an addition to standard malaria treatments in pre-elimination settings due to its pronounced activity against mature Plasmodium falciparum gametocytes, the parasite stage ...

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