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Browsing Research Articles (University of Pretoria) by Subject "G2019S mutation"

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Frequency of the LRRK2 G2019S mutation in South African patients with Parkinson’s disease

Du Toit, Nicola; Van Coller, Riaan; Anderson, David G.; Carr, Jonathan; Bardien, Soraya (Springer, 2019-10)

G2019S in LRRK2 is the most common mutation associated with Parkinson’s disease (PD). Highest frequencies are in North African Arabic (30–41%) and Ashkenazi Jewish (6–30%) populations, mostly due to founder effects. Here, ...

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