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Browsing Research Articles (University of Pretoria) by Subject "Vaccine efficacy"

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Efficacy and immunogenicity of two or three dose rotavirus-vaccine regimen in South African children over two consecutive rotavirus-seasons : a randomized, double-blind, placebo-controlled trail

Madhi, Shabir A.; Kirsten, M.; Louw, C.; Bos, P.; Aspinall, S.; Bouckenooghe, Alain; Neuzil, Kathleen M.; Steele, Andrew Duncan (Elsevier, 2012-04)

BACKGROUND: Human rotavirus vaccine (HRV; i.e., Rotarix) reduced the incidence of severe rotavirus gastroenteritis (RVGE) by 77% (95% Conficence interval: 56% to 88%) during the first year of life in South Africa. Persistence ...
Efficacy of a high potency O1 Manisa monovalent vaccine against heterologous challenge with foot-and-mouth disease virus of O/SEA/Mya-98 lineage in sheep

Singanallur, N.B.; Pacheco, J.M.; Arzt, J.; Stenfeldt, C.; Fosgate, Geoffrey Theodore; Rodriguez, L.; Vosloo, W. (Elsevier, 2017-09)

Potency tests for commercial oil-adjuvanted foot-and-mouth disease (FMD) vaccines are usually carried out in cattle, using a full dose (2 ml) of vaccine and homologous virus challenge. However, in sheep the recommended ...
Efficacy of primary series AZD1222 (ChAdOx1 nCoV-19) vaccination against SARS-CoV-2 variants of concern: Final analysis of a randomized, placebo-controlled, phase 1b/2 study in South African adults (COV005)

Koen, Anthonet L.; Izu, Alane; Baillie, Vicky; Kwatra, Gaurav; Cutland, Clare L.; Fairlie, Lee; Padayachee, Sherman D.; Dheda, Keertan; Barnabas, Shaun L.; Bhorat, Qasim Ebrahim; Briner, Carmen; Ahmed, Khatija; Bhikha, Sutika; Bhiman, Jinal N.; Du Plessis, Jeanine; Esmail, Aliasgar; Horne, Elizea; Hwa, Shi-Hsia; Oommen-Jose, Aylin; Lambe, Teresa; Laubscher, Matt; Malahleha, Mookho; Benade, Gabriella; McKenzie, Shakeel; Oelofse, Suzette; Patel, Faeezah; Pillay, Sureshnee; Rhead, Sarah; Rodel, Hylton; Taoushanis, Carol; Tegally, Houriiyah; Thombrayil, Asha; Villafana, Tonya L.; Gilbert, Sarah; Pollard, Andrew J.; Madhi, Shabir A. (Elsevier, 2023-05)

COVID-19 vaccine efficacy (VE) has been observed to vary against antigenically distinct SARS-CoV-2 variants of concern (VoC). Here we report the final analysis of VE and safety from COV005: a phase 1b/2, multicenter, ...

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Browsing Research Articles (University of Pretoria) by Subject "Vaccine efficacy"

Browsing Research Articles (University of Pretoria) by Subject "Vaccine efficacy"

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