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Browsing Research Articles (University of Pretoria) by Subject "Antimicrobial macrolide"

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Comparative genomic and metabolic analysis of Streptomyces sp. RB110 morphotypes illuminates genomic rearrangements and formation of a new 46-membered antimicrobial macrolide

Um, Soohyun; Guo, Huijuan; Thiengmag, Sirinthra; Benndorf, Rene; Murphy, Robert; Rischer, Maja; Braga, Daniel; Poulsen, Michael; De Beer, Z. Wilhelm; Lackner, Gerald; Beemelmanns, Christine (American Chemical Society, 2021-07)

Morphotype switches frequently occur in Actinobacteria and are often associated with disparate natural product production. Here, we report on differences in the secondary metabolomes of two morphotypes of a Streptomyces ...

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