Browsing Research Articles (University of Pretoria) by Title

Browsing Research Articles (University of Pretoria) by Title

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  • Transcriptional reprogramming during recovery from drought stress in Eucalyptus grandis 
    Teshome, Demissew Tesfaye; Zharare, Godfrey Elijah; Ployet, Raphael; Naidoo, Sanushka (Oxford University Press, 2023-06)
    The importance of drought as a constraint to agriculture and forestry is increasing with climate change. Genetic improvement of plants’ resilience is one of the mitigation strategies to curb this threat. Although recovery ...
  • Transcriptome analysis of an incompatible Persea americana-Phytophthora cinnamomi interaction reveals the involvement of SA- and JA-pathways in a successful defense response 
    Van den Berg, Noelani; Mahomed, Waheed; Olivier, Nicholas Abraham; Swart, Velushka; Crampton, Bridget Genevieve (Public Library of Science, 2018-10-17)
    Phytophthora cinnamomi Rands (Pc) is a hemibiotrophic oomycete and the causal agent of Phytophthora root rot (PRR) of the commercially important fruit crop avocado (Persea americana Mill.). Plant defense against pathogens ...
  • Transcriptome analysis of Eucalyptus grandis implicates brassinosteroid signaling in defense against myrtle rust (Austropuccinia psidii) 
    Swanepoel, Shae; Oates, Caryn Nicole; Shuey, Louise S.; Pegg, Geoff S.; Naidoo, Sanushka (Frontiers Media, 2021-12-08)
    Eucalyptus grandis, in its native Australian range, varies in resistance to Austropuccinia psidii (syn. Puccinia psidii). The biotrophic rust fungus, A. psidii is the causal agent of myrtle rust and poses a serious threat ...
  • Transcriptome analysis of the inflammatory responses of bovine mammary epithelial cells : exploring immunomodulatory target genes for bovine mastitis 
    Islam, Md.Aminul; Takagi, Michihiro; Fukuyama, Kohtaro; Komatsu, Ryoya; Albarracin, Leonardo; Nochi, Tomonori; Suda, Yoshihito; Ikeda-Ohtsubo, Wakako; Rutten, Victor P.M.G.; Van Eden, Willem; Villena, Julio; Aso, Hisashi; Kitazawa, Haruki (MDPI, 2020-03-09)
    Bovine mastitis is the inflammatory reaction of the mammary gland and is commonly caused by bacterial infections in high-yielding dairy cows. The detailed investigation of the immunotranscriptomic response of bovine ...
  • Transcriptome and comparative genomics analyses reveal new functional insights on key determinants of pathogenesis and interbacterial competition in Pectobacterium and Dickeya spp. 
    Bellieny-Rabelo, Daniel; Tanui, Collins Kipngetich; Miguel, Nikki; Kwenda, Stanford; Shyntum, Divine Yufetar; Moleleki, Lucy Novungayo (American Society for Microbiology, 2019-01)
    Soft-rot Enterobacteriaceae (SRE), typified by Pectobacterium and Dickeya genera, are phytopathogenic bacteria inflicting soft-rot disease in crops worldwide. By combining genomic information from 100 SRE with whole-transcriptome ...
  • Transcriptome and hormone profiling reveals Eucalyptus grandis defence responses against Chrysoporthe austroafricana 
    Mangwanda, Ronishree; Myburg, Alexander Andrew; Naidoo, Sanushka (BioMed Central, 2015-04-18)
    BACKGROUND : Eucalyptus species and interspecific hybrids exhibit valuable growth and wood properties that make them a highly desirable commodity. However, these trees are challenged by a wide array of biotic stresses ...
  • Transcriptome and proteome analysis of innate immune responses to inactivated Leptospira and bivalent Leptospira vaccines in canine 030-D cells 
    Novak, Andreja; Pennings, Jeroen; Van der Maas, Larissa; Meiring, Hugo; Ludwig, Irene; Verkoeijen, Saertje; Rutten, Victor P.M.G.; Broere, Femke; Sloots, Arjen (Nature Research, 2022-08-04)
    Mandatory potency testing of Leptospira vaccine batches relies partially on in vivo procedures, requiring large numbers of laboratory animals. Cell-based assays could replace in vivo tests for vaccine quality control if ...
  • The transcriptome of Pinus pinaster under Fusarium circinatum challenge 
    Hernandez-Escribano, Laura; Visser, Erik A.; Iturritxa, Eugenia; Raposo, Rosa; Naidoo, Sanushka (BioMed Central, 2020-01-08)
    BACKGROUND : Fusarium circinatum, the causal agent of pitch canker disease, poses a serious threat to several Pinus species affecting plantations and nurseries. Although Pinus pinaster has shown moderate resistance to F. ...
  • Transcriptome profiling of kisspeptin neurons from the mouse arcuate nucleus reveals new mechanisms in estrogenic control of fertility 
    Gocz, Balazs; Rumpler, Eva; Sarvari, Miklos; Skrapits, Katalin; Takacs, Szabolcs; Farkas, Imre; Csillag, Veronika; Trinh, Sarolta H.; Bardoczi, Zsuzsanna; Solymosi, Norbert; Poliska, Szilard; Bartoloni, Lucia; Zouaghi, Yassine; Messina, Andrea; Pitteloud, Nelly; Anderson, Ross Calley; Millar, Robert P.; Quinton, Richard; Manchishi, Stephen M.; Colledge, William H.; Hrabovszky, Erik (National Academy of Sciences, 2022-06-28)
    Kisspeptin neurons in the mediobasal hypothalamus (MBH) are critical targets of ovarian estrogen feedback regulating mammalian fertility. To reveal molecular mechanisms underlying this signaling, we thoroughly characterized ...
  • Transcriptome profiling of potato (Solanum tuberosum L.) responses to root-knot nematode (Meloidogyne javanica) infestation during a compatible interaction 
    Macharia, Teresia Nyambura; Bellieny-Rabelo, Daniel; Moleleki, Lucy Novungayo (MDPI, 2020-09)
    Root-knot nematode (RKN) Meloidogyne javanica presents a great challenge to Solanaceae crops, including potato. In this study, we investigated transcriptional responses of potato roots during a compatible interaction ...
  • Transcriptome profiling Reveals the EanI/R quorum sensing regulon in Pantoea ananatis LMG 2665(T) 
    Sibanda, Siphathele; Kwenda, Stanford; Tanui, Collins Kipngetich; Shyntum, Divine Yufetar; Coutinho, Teresa A.; Moleleki, Lucy Novungayo (Elsevier, 2018-03)
    Please read abstract in the article.
  • Transcriptome responses of an ungrafted Phytophthora root rot tolerant avocado (Persea americana) rootstock to flooding and Phytophthora cinnamomi 
    Reeksting, Bianca J.; Olivier, Nicholas Abraham; Van den Berg, Noelani (BioMed Central, 2016-09-22)
    BACKGROUND : Avocado (Persea americana Mill.) is a commercially important fruit crop worldwide. A major limitation to production is the oomycete Phytophthora cinnamomi, which causes root rot leading to branch-dieback and ...
  • A transcriptome-wide association study among 97,898 women to identify candidate susceptibility genes for epithelial ovarian cancer risk 
    Lu, Yingchang; Beeghly-Fadiel, Alicia; Wu, Lang; Guo, Xingyi; Li, Bingshan; Schildkraut, Joellen M.; Im, HaeKyung; Chen, Yian A.; Permuth, Jennifer B.; Reid, Brett M.; Teer, Jamie K.; Moysich, Kirsten B.; Andrulis, Irene L.; Anton-Culver, Hoda; Arun, Banu K.; Bandera, Elisa V.; Barkardottir, Rosa B.; Barnes, Daniel R.; Benitez, Javier; Bjorge, Line; Brenton, James; Butzow, Ralf; Caldes, Trinidad; Caligo, Maria A.; Campbell, Ian; Chang-Claude, Jenny; Claes, Kathleen B.M.; Couch, Fergus J.; Cramer, Daniel W.; Daly, Mary B.; DeFazio, Anna; Dennis, Joe; Diez, Orland; Domchek, Susan M.; Dörk, Thilo; Easton, Douglas F.; Eccles, Diana M.; Fasching, Peter A.; Fortner, Renée T.; Fountzilas, George; Friedman, Eitan; Ganz, Patricia A.; Garber Judy; Giles, Graham G.; Godwin, Andrew K.; Goldgar, David E.; Goodman, Marc T.; Greene, Mark H.; Gronwald, Jacek; Hamann, Ute; Heitz, Florian; Hildebrandt, Michelle A.T.; Høgdall, Claus K.; Hollestelle, Antoinette; Hulick, Peter J.; Huntsman, David G.; Imyanitov, Evgeny N.; Isaacs, Claudine; Jakubowska, Anna; James, Paul; Karlan, Beth Y.; Kelemen, Linda E.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Kwong, Ava; Le, Nhu D.; Leslie, Goska; Lesueur, Fabienne; Levine, Douglas A.; Mattiello, Amalia; May, Taymaa; McGuffog, Lesley; McNeish, Iain A.; Merritt, Melissa A.; Modugno, Francesmary; Montagna, Marco; Neuhausen, Susan L.; Nevanlinna, Heli; Nielsen, Finn C.; Nikitina-Zake, Liene; Nussbaum, Robert L.; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I.; Olson, Sara H.; Olsson, Håkan K.; Osorio, Ana; Park, Sue K.; Parsons, Michael T.; Peeters, Petra H.M.; Pejovic, Tanja; Peterlongo, Paolo; Phelan, Catherine M.; Pujana, Miquel Angel; Ramus, Susan J.; Rennert, Gad; Risch, Harvey; Rodriguez, Gustavo C.; Rodríguez-Antona, Cristina; Romieu, Isabelle; Rookus, Matti A.; Rossing, Mary Anne; Rzepecka, Iwona K.; Sandler, Dale P.; Schmutzler, Rita K.; Setiawan, Veronica W.; Sharma, Priyanka; Sieh, Weiva; Simard, Jacques; Singer, Christian F.; Song, Honglin; Southey, Melissa C.; Spurdle, Amanada B.; Sutphen, Rebecca; Swerdlow, Anthony J.; Teixeira, Manuel R.; Teo, Soo H.; Thomassen, Mads; Tischkowitz, Marc; Toland, Amanda E.; Trichopoulou, Antonia; Tung, Nadine; Tworoger, Shelley S.; Jansen van Rensburg, Elizabeth; Vanderstichele, Adriaan; Vega, Ana; Edwards, Digna Velez; Webb, Penelope M.; Weitzel, Jeffrey N.; Wentzensen, Nicolas; White, Emily; Wolk, Alicja; Wu, Anna H.; Yannoukakos, Drakoulis; Zorn, Kristin K.; Gayther, Simon A.; Antoniou, Antonis C.; Berchuck, Andrew; Goode, Ellen L.; Chenevix-Trench, Georgia; Sellers, Thomas A.; Pharoah, Paul D.P.; Zheng, Wei; Long, Jirong (American Association for Cancer Research, 2018-09)
    Large-scale genome-wide association studies (GWAS) have identified approximately 35 loci associated with epithelial ovarian cancer (EOC) risk. The majority of GWAS-identified disease susceptibility variants are located in ...
  • Transcriptome-wide association study of breast cancer risk by estrogen-receptor status 
    Feng, Helian; Gusev, Alexander; Pasaniuc, Bogdan; Wu, Lang; Long, Jirong; Abu-full, Zomoroda; Aittomäki, Kristiina; Andrulis, Irene L.; Anton-Culver, Hoda; Antoniou, Antonis C.; Arason, Adalgeir; Arndt, Volker; Aronson, Kristan J.; Arun, Banu K.; Asseryanis, Ella; Auer, Paul L.; Azzollini, Jacopo; Balmana, Judith; Barkardottir, Rosa B.; Barnes, Daniel R.; Barrowdale, Daniel; Beckmann, Matthias W.; Behrens, Sabine; Benitez, Javier; Bermisheva, Marina; Białkowska, Katarzyna; Blanco, Ana; Blomqvist, Carl; Boeckx, Bram; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; Bonanni, Bernardo; Borg, Ake; Brauch, Hiltrud; Brenner, Hermann; Briceno, Ignacio; Broeks, Annegien; Bruning, Thomas; Burwinkel, Barbara; Cai, Qiuyin; Caldés, Trinidad.; Caligo, Maria A.; Campbell, Ian; Canisius, Sander; Campa, Daniele; Carter, Brian D.; Carter, Jonathan; Castelao, Jose E.; Chang-Claude, Jenny; Chanock, Stephen J.; Christiansen, Hans; Chung, Wendy K.; Claes, Kathleen B.M.; Clarke, Christine L.; Couch, Fergus J.; Cox, Angela; Cross, Simon S.; Cybulski, Cezary; Czene, Kamila; Daly, Mary B.; De la Hoya, Miguel; De Leeneer, Kim; Dennis, Joe; Devilee, Peter; Diez, Orland; Domchek, Susan M.; Dork, Thilo; Dos-Santos-Silva, Isabel; Dunning, Alison M.; Dwek, Miriam; Eccles, Diana M.; Ejlertsen, Bent; Ellberg, Carolina; Engel, Christoph; Eriksson, Mikael; Fasching, Peter A.; Fletcher, Olivia; Flyger, Henrik; Fostira, Florentia; Friedman, Eitan; Fritschi, Lin; Frost, Debra; Gabrielson, Marike; Ganz, Patricia A.; Gapstur, Susan M.; Garber, Judy; Garcia-Closas, Montserrat; Garcia-Saenz, Jose A.; Gaudet, Mia M.; Giles, Graham G.; Glendon, Gord; Godwin, Andrew K.; Goldberg, Mark S.; Goldgar, David E.; Gonzalez-Neira, Anna; Greene, Mark H.; Gronwald, Jacek; Guénel, Pascal; Haiman, Christopher A.; Hall, Per; Hamann, Ute; Hake, Christopher; He, Wei; Heyworth, Jane; Hogervorst, Frans B.L.; Hollestelle, Antoinette; Hooning, Maartje J.; Hoover, Robert N.; Hopper, John L.; Huang, Guanmengqian; Humphreys, Keith; Imyanitov, Evgeny N.; Isaacs, Claudine; Jakimovska, Milena; Jakubowska, Anna; James, Paul; Janavicius, Ramunas; Jankowitz, Rachel C.; John, Esther M.; Johnson, Nichola; Joseph, Vijai; Jung, Audrey; Karlan, Beth Y.; Khusnutdinova, Elza; Kiiski, Johanna I.; Konstantopoulou, Irene; Kristensen, Vessela; Laitman, Yael; Lambrechts, Diether; Lazaro, Conxi; Leroux, Dominique; Leslie, Goska; Lester, Jenny; Lesueur, Fabienne; Lindor, Noralane; Lindstrom, Sara; Lo, Wing-Yee; Loud, Jennifer T.; Lubinski, Jan; Makalic, Enes; Mannermaa, Arto; Manoochehri, Mehdi; Manoukian, Siranoush; Margolin, Sara; Martens, John W.M.; Martinez, Maria E.; Matricardi, Laura; Maurer, Tabea; Mavroudis, Dimitrios; McGuffog, Lesley; Meindl, Alfons; Menon, Usha; Michailidou, Kyriaki; Kapoor, Pooja M.; Miller, Austin; Montagna, Marco; Moreno, Fernando; Moserle, Lidia; Mulligan, Anna M.; Muranen, Taru A.; Nathanson, Katherine L.; Neuhausen, Susan L.; Nevanlinna, Heli; Nevelsteen, Ines; Nielsen, Finn C.; Nikitina-Zake, Liene; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I.; Olsson, Hakan; Osorio, Ana; Papp, Janos; Park-Simon, Tjoung-Won; Parsons, Michael T.; Pedersen, Inge S.; Peixoto, Ana; Peterlongo, Paolo; Peto, Julian; Pharoah, Paul D.P.; Phillips, Kelly-Anne; Plaseska-Karanfilska, Dijana; Poppe, Bruce; Pradhan, Nisha; Prajzendanc, Karolina; Presneau, Nadege; Punie, Kevin; Pylkäs, Katri; Radice, Paolo; Rantala, Johanna; Rashid, Muhammad Usman; Rennert, Gad; Risch, Harvey A.; Robson, Mark; Romero, Atocha; Saloustros, Emmanouil; Sandler, Dale P.; Santos, Catarina; Sawyer, Elinor J.; Schmidt, Marjanka K.; Schmidt, Daniel F.; Schmutzler, Rita K.; Schoemaker, Minouk J.; Scott, Rodney J.; Sharma, Priyanka; Shu, Xiao-Ou; Simard, Jacques; Singer, Christian F.; Skytte, Anne-Bine; Soucy, Penny; Southey, Melissa C.; Spinelli, John J.; Spurdle, Amanda B.; Stone, Jennifer; Swerdlow, Anthony J.; Tapper, William J.; Taylor, Jack A.; Teixeira, Manuel R.; Terry, Mary Beth; Teule, Alex; Thomassen, Mads; Thöne, Kathrin; Thull, Darcy L.; Tischkowitz, Marc; Toland, Amanda E.; Tollenaar, Rob A.E.M.; Torres, Diana; Truong, Therese; Tung, Nadine; Vachon, Celine M.; Van den Ouweland, Ans M.W.; Van Asperen, Christi J.; Jansen van Rensburg, Elizabeth; Vega, Ana; Viel, Alessandra; Vieiro-Balo, Paula; Wang, Qin; Wappenschmidt, Barbara; Weinberg, Clarice R.; Weitzel, Jeffrey N.; Wendt, Camilla; Winqvist, Robert; Yang, Xiaohong R.; Yannoukakos, Drakoulis; Ziogas, Argyrios; Milne, Roger L.; Easton., Douglas F.; Chenevix-Trench, Georgia; Zheng, Wei; Kraft, Peter; Jiang, Xia (Wiley, 2020-07)
    Previous transcriptome-wide association studies (TWAS) have identified breast cancer risk genes by integrating data from expression quantitative loci and genome-wide association studies (GWAS), but analyses of breast ...
  • Transcriptomic analysis of a Sorghum bicolor landrace identifies a role for beta-alanine betaine biosynthesis in drought tolerance 
    Devnarain, Natrisha; Crampton, Bridget Genevieve; Olivier, Nicholas Abraham; Van der Westhuyzen, Chris; Becker, John V.W.; O'Kennedy, Martha Magaretha (Elsevier, 2019-12)
    Sorghum is indigenous to Africa and a remarkably drought tolerant cereal crop. In this study, the genetic response mechanisms involved in sorghum's tolerance to progressive water deficit and re-watering were investigated ...
  • Transcriptomic analysis of Ehrlichia ruminantium during the developmental stages in bovine and tick cell culture 
    Tjale, Mabotse A.; Pretorius, Alri; Josemans, Antoinette; Van Kleef, Mirinda; Liebenberg, Junita (Elsevier, 2018-01)
    The use of bioinformatics tools to search for possible vaccine candidates has been successful in recent years. In an attempt to search for additional vaccine candidates or improve the current heartwater vaccine design, a ...
  • Transcriptomic analysis of salivary glands of ornithodoros brasiliensis aragao, 1923, the agent of a neotropical tick-toxicosis syndrome in humans 
    Reck, Jose; Webster, Anelise; Dall’Agnol, Bruno; Pienaar, Ronel; De Castro, Minique H.; Featherston, Jonathan; Mans, Ben J. (Barend Johannes) (Frontiers Media, 2021-08-06)
    Tick salivary glands produce and secrete a variety of compounds that modulate host responses and ensure a successful blood meal. Despite great progress made in the identification of ticks salivary compounds in recent years, ...
  • Transcriptomic analysis of the poultry red mite, Dermanyssus gallinae, across all stages of the lifecycle 
    Bartley, Kathryn; Chen, Wan; Mills, Richard I. Lloyd; Nunn, Francesca; Price, Daniel R.G.; Rombauts, Stephane; Van de Peer, Yves; Roy, Lise; Nisbet, Alasdair J.; Burgess, Stewart T.G. (BMC, 2021-04)
    BACKGROUND: The blood feeding poultry red mite (PRM), Dermanyssus gallinae, causes substantial economic damage to the egg laying industry worldwide, and is a serious welfare concern for laying hens and poultry house workers. ...
  • The transcriptomic changes associated with the development of social parasitism in the honeybee Apis mellifera capensis 
    Aumer, Denise; Mumoki, F.N. (Fiona); Pirk, Christian Walter Werner; Moritz, Robin F.A. (Springer, 2018-04)
    Social insects are characterized by the division of labor. Queens usually dominate reproduction, whereas workers fulfill non-reproductive age-dependent tasks to maintain the colony. Although workers are typically sterile, ...
  • Transcriptomic responses of a simplified soil microcosm to a plant pathogen and its biocontrol agent reveal a complex reaction to harsh habitat 
    Perazzolli, Michele; Herrero, Noemí; Sterck, Lieven; Lenzi, Luisa; Pellegrini, Alberto; Puopolo, Gerardo; Van de Peer, Yves; Pertot, Ilaria (BioMed Central, 2016-10-27)
    BACKGROUND : Soil microorganisms are key determinants of soil fertility and plant health. Soil phytopathogenic fungi are one of the most important causes of crop losses worldwide. Microbial biocontrol agents have been ...