Individuals struggle to attain optimal wellness and health levels due to unhealthy lifestyle behaviour. A holistic wellness model was developed in this study to provide a framework for a cross-sectional survey to assess the wellness behaviour and health risk levels of managers in two South African universities. A census was done on the total population of 324 and responses were received from 89 managers. The study employed descriptive and inferential statistical procedures to analyse the quantitative data. The findings suggested that the managers had high levels of wellness behaviour and low levels of health risks. Physical fitness and nutrition as well as medical self-care wellness behaviour levels were identified as weaknesses among managers, for which urgent interventions are required.