The mechanism of action of oral antidiabetic drugs : a review of recent literature

Bosenberg, Liesel H.; Van Zyl, Danie G.

dc.contributor.author	Bosenberg, Liesel H.
dc.contributor.author	Van Zyl, Danie G.
dc.date.accessioned	2009-05-25T09:31:57Z
dc.date.available	2009-05-25T09:31:57Z
dc.date.issued	2008-12
dc.description.abstract	Type 2 diabetes mellitus (DM) is a disorder that is placing an increasing burden on health service delivery worldwide. Consequently, it has become increasingly important that physicians who treat such patients have a good knowledge of antidiabetic drugs that are currently available or will come onto the market. This article presents an overview of all the major drug classes as well as some information on pharmacokinetics, pharmacodynamics, side-effect profiles and indications for use.	en_US
dc.identifier.citation	Bosenberg, LH & Van Zyl, DG 2008, 'The mechanism of action of oral antidiabetic drugs: a review of recent literature', Journal of Endocrinology, Metabolism and Diabetes of South Africa, vol. 13, no. 3, pp. 80-88. [http://www.hmpg.co.za/journaldetail.php?journalno=9]	en_US
dc.identifier.issn	1608-9677
dc.identifier.uri	http://hdl.handle.net/2263/10139
dc.language.iso	en	en_US
dc.publisher	Health & Medical Publishing Group	en_US
dc.rights	Health & Medical Publishing Group	en_US
dc.subject	Antidiabetic drugs	en_US
dc.subject	Oral drugs	en_US
dc.subject	Type 2 diabetes mellitus	en_US
dc.subject	Physician's knowledge	en_US
dc.subject	Drug knowledge	en_US
dc.subject	Drug mechanism	en_US
dc.subject	Pharmacokinetics	en_US
dc.subject	Pharmacodynamics	en_US
dc.subject	Side effects	en_US
dc.subject	Literature review	en_US
dc.subject	Insulin secretagogues	en_US
dc.subject	Sulfonylureas	en_US
dc.subject	Glibenclamide	en_US
dc.subject	Gliclazide	en_US
dc.subject	Glipizide	en_US
dc.subject	Glimepiride	en_US
dc.subject	Rapid-acting prandial insulin	en_US
dc.subject	Repaglinide	en_US
dc.subject	Nateglinide	en_US
dc.subject	Insulin releasers	en_US
dc.subject	Insulin sensitisers	en_US
dc.subject	Biguanides	en_US
dc.subject	Metformin	en_US
dc.subject	Thiazolidinediones	en_US
dc.subject	Pioglitazone	en_US
dc.subject	Rosiglitazone	en_US
dc.subject	Glucosidase inhibitors	en_US
dc.subject	Acarbose	en_US
dc.subject	Incretins	en_US
dc.subject	Exendin-4	en_US
dc.subject	Liraglutide	en_US
dc.subject	Vildagliptin	en_US
dc.subject	Sitagliptin	en_US
dc.subject	Amylin analogues	en_US
dc.subject	Pramlintide	en_US
dc.subject	Treatment modalities	en_US
dc.subject.lcsh	Diabetics
dc.subject.lcsh	Therapeutics
dc.subject.lcsh	Pharmacokinetics
dc.subject.lcsh	Drugs -- Physiological effect
dc.subject.mesh	Diabetes Mellitus, Type 2
dc.title	The mechanism of action of oral antidiabetic drugs : a review of recent literature	en_US
dc.type	Article	en_US