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Browsing Veterinary Science by Author "Mabeta, Peaceful Lucy"
Now showing items 1-11 of 11
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Ionescu, G.; Mabeta, Peaceful Lucy; Dippenaar, Nola; Muir, T.; Fourie, P.; Shelver, Graham (Health and Medical Publishing Group, 2008-07)No abstract available
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Mabeta, Peaceful Lucy (Krakow Polish Physiological Society, 2013)Bleomycin is an antineoplastic drug that has recently been employed to treat haemangiomas, the most common vascular tumors of infancy, with very good results. To better understand the mechanism of bleomycin in ...
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Mabeta, Peaceful Lucy (Elsevier, 2014-06)The phosphoinositide 3-kinase (PI3k) signaling pathway is involved in the regulation of numerous cellular activities. The pathway has also been implicated in the development of various tumors. In the context of vascular ...
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Mabeta, Peaceful Lucy; Davis, P.F. (Health and Medical Publishing Group, 2008-07)Haemangiomas are neoplasms of the vasculature frequently encountered in paediatrics which, although benign, may present with serious complications. The potential beneficial effects of intralesional bleomycin injection (IBI) ...
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Mphahlele, Malose J.; Khoza, Tebogo A.; Mabeta, Peaceful Lucy (MDPI Publishing, 2017)Herein we describe the synthesis and evaluation of a series of novel 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinazolin-1-ones for in vitro cytotoxicity against three human cancer cell lines as well as for potential antimalarial ...
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Mphahlele, Malose Jack; Maluleka, Marole Maria; Makhafola, Tshepiso Jan; Mabeta, Peaceful Lucy (MDPI, 2014-11)Direct one-pot base-promoted conjugate addition–elimination of 6,8-dibromo-4- chloroquinoline-3-carbaldehyde with methyl mercaptoacetate and subsequent cyclization afforded methyl [(6,8-dibromothieno[3,2-c]quinoline)]- ...
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Forcados, Gilead Ebiegberi; Mabeta, Peaceful Lucy; James, Dorcas Bolanle; Sallau, Abdullahi Balarabe; Muhammad, Aliyu (Taylor and Francis, 2017-04)Breast cancer remains a burden in both developed and developing countries, with higher mortality in developing countries. Attempts to eradicate cancer have not been successful despite the progress made in the development ...
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Mabeta, Peaceful Lucy (De Gruyter Open, 2016-09)PF573,228 is a compound that targets focal adhesion kinase (FAK), a non-receptor protein kinase, which is over-expressed in various tumors. The aim of this study was to evaluate the effects of PF573,228 on the cells ...
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Mabeta, Peaceful Lucy (University of Pretoria, 2006-03-29)Radiotherapy for cancer produces prolonged testicular damage that is manifested by failure of spermatogenic recovery following treatment. It has thus become important to develop methods to induce the recovery of spermatogenesis, ...
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Mabeta, Peaceful Lucy; Dippenaar, Nola; Shelver, Graham (PharmSciDirect, 2012-10-13)Bleomycin is an anti-neoplastic drug that has recently been used for the treatment of vascular anomalies. The plasma concentration of bleomycin following intralesional injection into vascular lesions is unknown. An expedient ...
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Mukorera, Varaidzo; Kirberger, Robert M.; Mabeta, Peaceful Lucy; Dvir, Eran (Wiley-Blackwell, 2013-11)BACKGROUND : Vascular endothelial growth factor (VEGF) is a potent proangiogenic factor associated with tumor development.Spirocerca lupi is a nematode of canids that induces an esophageal nodule that progresses to a ...
Now showing items 1-11 of 11