Dvir, Eran; Elman, Anat; Simmons, Danielle; Shapiro, Israel; Duvdevani, Revital; Dahan, Arik; Hoffman, Amnon; Friedman, Jonathan E.
(Blackwell, 2007-06)
DP-155 is a lipid prodrug of indomethacin that comprises the latter conjugated to lecithin at position sn-2 via a 5-carbon length linker. It is cleaved by phospholipase A2 (PLA)2 to a greater extent than similar compounds ...