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Browsing Psychiatry by Subject "Low-density lipoprotein-cholesterol (LDL-C)"

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The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia - a post-hoc analysis of a phase 3, single-arm, open-label trial

Stefanutti, Claudia; Blom, Dirk J.; Averna, Maurizio R.; Meagher, Emma A.; Theron, Hendrik Du Toit; Marais, A. David; Hegele, Robert A.; Sirtori, Cesare R.; Shah, Prediman K.; Gaudet, Daniel; Vigna, Giovanni B.; Sachais, B.S.; Di Giacomo, S.; Du Plessis, Anna M.E.; Bloeden, LeAnne T.; Balser, J.; Rader, Daniel J.; Cuchel, Marina (Elsevier, 2015-06)

OBJECTIVE : Lomitapide (a microsomal triglyceride transfer protein inhibitor) is an adjunctive treatment for homozygous familial hypercholesterolaemia (HoFH), a rare genetic condition characterised by elevated low-density ...

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